Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PARL | Q9H300 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 3/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972689 | 0.84 | ALDH1A1 (0.69) | ALDH1A1MAPTPOLBMMP2MEN1 | |
| SCHEMBL6797308 | 0.84 | MMP2 (0.58) | ALDH1A1MAPTPOLBMMP2MEN1 | |
| SCHEMBL9491573 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTPOLBMMP2MEN1 | |
| SCHEMBL10676845 | 0.76 | MEN1 (0.51) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL10681934 | 0.74 | RXFP1 (0.48) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL8798641 | 0.74 | CA2 (0.47) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL10677902 | 0.73 | HSD17B10 (0.40) | ALDH1A1MAPTPOLBMMP2MEN1 | |
| SCHEMBL8799405 | 0.73 | POLB (0.37) | ALDH1A1MAPTPOLBMMP2MEN1 | |
| SCHEMBL8788603 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL8799012 | 0.73 | CA2 (0.46) | ALDH1A1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025589-A1 | 2-Thiohydantoine derivative compounds and use thereof for the treatment of diabetes | LABORATOIRES FOURNIER S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
| US-20040116617-A1 | Polymer-supported arylbis(perfluoroalkylsulfonyl)-methane | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-06-17 | — | — | US | disclosed |
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |
| CN-1500081-A | Thiohydantonins and use thereof for treating diabetes | ʵ���Ҹ���Ү��˾ | 2004-05-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025589-A1 | 2-Thiohydantoine derivative compounds and use thereof for the treatment of diabetes | LIPC, CYP4F2, SLC5A2 | ALDH1A1 452/4885MAPT 4311/4885POLB 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.