Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333674 | 0.89 | OPRM1 (0.49) | MAPTALDH1A1LMNATHRBSMN1; SMN2 | |
| SCHEMBL5954820 | 0.81 | HPGD (0.50) | RAB9AHPGDNPC1CRHBPCRHR2 | |
| SCHEMBL1035137 | 0.80 | OPRM1 (0.60) | MAPTLMNASMN1; SMN2OPRM1MEN1 | |
| SCHEMBL11563510 | 0.75 | OPRM1 (0.45) | MAPTALDH1A1LMNASMN1; SMN2OPRM1 | |
| SCHEMBL25492303 | 0.75 | GAA (0.44) | MAPTLMNATHRBADAM17SMN1; SMN2 | |
| SCHEMBL2985764 | 0.74 | CYP2D6 (0.60) | ALDH1A1LMNASMN1; SMN2HTTOPRM1 | |
| SCHEMBL11565880 | 0.74 | OPRM1 (0.57) | ALDH1A1LMNASMN1; SMN2HTTMAPK1 | |
| SCHEMBL11563599 | 0.74 | OPRM1 (0.50) | RAB9AHPGDMAPTALDH1A1LMNA | |
| SCHEMBL9091689 | 0.74 | RAB9A (1.00) | RAB9AHPGDNPC1CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL11455428 | 0.74 | CYP2D6 (0.58) | ALDH1A1LMNASMN1; SMN2HTTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025589-A1 | 2-Thiohydantoine derivative compounds and use thereof for the treatment of diabetes | LABORATOIRES FOURNIER S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025589-A1 | 2-Thiohydantoine derivative compounds and use thereof for the treatment of diabetes | LIPC, CYP4F2, SLC5A2 | RAB9A 3994/4885HPGD 892/4885NPC1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.