Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065319 | 0.90 | LMNA (0.32) | — | |
| SCHEMBL9752462 | 0.86 | LMNA (0.38) | ADORA2AADORA2B | |
| SCHEMBL5031647 | 0.84 | BTK (0.30) | — | |
| SCHEMBL6756343 | 0.83 | RNASE1 (0.36) | — | |
| SCHEMBL28141801 | 0.80 | — | — | |
| SCHEMBL10381790 | 0.78 | ADORA1 (0.43) | ADORA2AADORA2B | |
| SCHEMBL8227198 | 0.77 | PYGM (0.37) | — | |
| SCHEMBL5031652 | 0.76 | — | — | |
| SCHEMBL8970900 | 0.74 | SLC29A1 (0.37) | ADORA2AADORA2B | |
| SCHEMBL11430666 | 0.73 | LMNA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611249-A4 | OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA | ISIS PHARMACEUTICALS INC (US) | 2006-06-28 | — | — | EP | disclosed |
| EP-1611249-A1 | OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA | ISIS PHARMACEUTICALS, INC. (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1442046-A4 | MAMMALIAN C-TYPE LECTINS | IMMUNEX CORP (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004097049-A1 | OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA | ISIS PHARMACEUTICALS, INC. (US) | 2004-11-11 | — | — | WO | disclosed |
| EP-1442046-A2 | MAMMALIAN C-TYPE LECTINS | Immunex CorporatioN (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1064402-A4 | ANTISENSE MODULATION OF LFA-3 | ISIS PHARMACEUTICALS INC (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2003031578-A2 | MAMMALIAN C-TYPE LECTINS | IMMUNEX CORPORATION (US) | 2003-04-17 | — | — | WO | disclosed |
| EP-1086116-A1 | COMPOSITIONS AND METHODS FOR THE PULMONARY DELIVERY OF NUCLEIC ACIDS | ISIS PHARMACEUTICALS, INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-1064402-A1 | ANTISENSE MODULATION OF LFA-3 | ISIS PHARMACEUTICALS, INC. (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-1064403-A1 | ANTISENSE MODULATION OF PECAM-1 | ISIS PHARMACEUTICALS, INC. (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-1003916-A1 | ANTISENSE OLIGONUCLEOTIDE COMPOSITIONS AND METHODS FOR THE MODULATION OF JNK PROTEINS | ISIS PHARMACEUTICALS, INC. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999060010-A1 | COMPOSITIONS AND METHODS FOR THE PULMONARY DELIVERY OF NUCLEIC ACIDS | ISIS PHARMACEUTICALS, INC. (US) | 1999-11-25 | — | — | WO | disclosed |
| WO-1999047707-A1 | ANTISENSE MODULATION OF LFA-3 | ISIS PHARMACEUTICALS, INC. (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999047708-A1 | ANTISENSE MODULATION OF PECAM-1 | ISIS PHARMACEUTICALS, INC. (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999011820-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION AND QUANTITATION OF DELETION SEQUENCE OLIGONUCLEOTIDES IN SYNTHETIC OLIGONUCLEOTIDE PREPARATIONS | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-11 | — | — | WO | disclosed |
| WO-1999009214-A1 | ANTISENSE OLIGONUCLEOTIDE COMPOSITIONS AND METHODS FOR THE MODULATION OF JNK PROTEINS | ISIS PHARMACEUTICALS, INC. (US) | 1999-02-25 | — | — | WO | disclosed |