Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480508 | 0.75 | TDP1 (0.54) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL330322 | 0.75 | FBP1 (0.41) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL11039735 | 0.74 | TDP1 (0.38) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL11591390 | 0.73 | TDP1 (0.51) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL7876673 | 0.73 | MEN1 (0.57) | TDP1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5961594 | 0.71 | TDP1 (0.46) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL1361250 | 0.70 | ALDH1A1 (0.44) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL147513 | 0.68 | ALDH1A1 (0.40) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL16174996 | 0.68 | TSHR (0.60) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL3480527 | 0.68 | TDP1 (0.44) | CYP3A4TDP1ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076053-B1 | 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-11-29 | — | — | EP | disclosed |