Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595121 | 0.76 | GPR35 (0.43) | LIPGGPR35TYRTP53CYP3A4 | |
| SCHEMBL12279155 | 0.74 | GPR35 (0.42) | LIPGGPR35TYRTP53CYP3A4 | |
| SCHEMBL14889282 | 0.73 | GPR35 (0.37) | LIPGGPR35TYRTP53CYP3A4 | |
| SCHEMBL14889177 | 0.73 | GPR35 (0.37) | LIPGGPR35TYRTP53CYP3A4 | |
| SCHEMBL1253768 | 0.73 | GPR35 (0.51) | LIPGGPR35TYRTP53CYP3A4 | |
| SCHEMBL1253645 | 0.73 | GPR35 (0.51) | LIPGGPR35TYRTP53CYP3A4 | |
| SCHEMBL25229247 | 0.72 | GPR35 (0.51) | LIPGGPR35TYRTP53CYP3A4 | |
| SCHEMBL9347729 | 0.72 | CYP2A6 (0.55) | LIPGGPR35TP53MAPTCYSLTR2 | |
| SCHEMBL991334 | 0.72 | GPR35 (0.41) | LIPGGPR35TYRTP53CYP3A4 | |
| SCHEMBL1156901 | 0.72 | GPR35 (0.51) | LIPGGPR35TYRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778695-B1 | POLYMERS OF THIENO[2,3-b]THIOPHENE | MERCK PATENT GMBH (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-8114316-B2 | Monomers, oligomers and polymers of thieno[2,3-b]thiophene | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-8114316-B2 | Monomers, oligomers and polymers of thieno[2,3-b]thiophene | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20090072200-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF THIENO[2,3-b]THIOPHENE | FLEXENABLE TECHNOLOGY LIMITED (GB) | 2009-03-19 | — | — | US | disclosed |
| US-20090072200-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF THIENO[2,3-b]THIOPHENE | FLEXENABLE TECHNOLOGY LIMITED (GB) | 2009-03-19 | — | — | US | disclosed |
| EP-1778695-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF THIENO[2,3-b]THIOPHENE | Merck Patent GmbH (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006021277-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF THIENO[2,3-b]THIOPHENE | MERCK PATENT GMBH (DE) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090072200-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF THIENO[2,3-b]THIOPHENE | FHIT, NLRP3, RFT1 | LIPG 2777/4885GPR35 3614/4885TYR 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.