SCHEMBL5956958

SCHEMBL5956958

Brc1ccc(N(c2ccccc2)c2cc3ccccc3c3ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
RXFP1 Q9HBX9 1/20 0.40
TRPM4 Q8TD43 1/20 0.36
ALDH1A1 P00352 6/20 0.35
HSD17B10 Q99714 3/20 0.35
HIF1A Q16665 1/20 0.35
CYP1B1 Q16678 1/20 0.35
CYP2A6 P11509 2/20 0.34
TDP1 Q9NUW8 3/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
APAF1 O14727 1/20 0.33
CASP3 P42574 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17740549 0.95 ALDH1A1 (0.41) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL127264 0.95 MEN1 (0.37) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL5957022 0.93 TRPM4 (0.38) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL29993540 0.92 ALDH1A1 (0.46) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL17165568 0.92 ALDH1A1 (0.46) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL12476233 0.92 ALDH1A1 (0.46) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL14069628 0.91 TRPM4 (0.42) MEN1KMT2ATRPM4ALDH1A1HSD17B10
SCHEMBL12333196 0.90 ALDH1A1 (0.42) MEN1KMT2ATRPM4ALDH1A1HSD17B10
SCHEMBL13720442 0.90 ALDH1A1 (0.42) MEN1KMT2ATRPM4ALDH1A1HSD17B10
SCHEMBL13721283 0.90 ALDH1A1 (0.42) MEN1KMT2ATRPM4ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106986811-B Organic compound and organic light emitting diode using the same 乐金显示有限公司 2020-08-21 CN disclosed
EP-3489325-B1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO LTD (KR) 2020-06-10 EP disclosed
EP-3489325-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG Display Co., Ltd. (KR) 2019-05-29 EP disclosed
EP-2881446-B1 Organic compound and organic light emitting diode using the same LG DISPLAY CO LTD (KR) 2019-01-09 EP disclosed
CN-104693105-B Organic compound and organic light emitting diode using the same 乐金显示有限公司 2018-12-04 CN disclosed
CN-106986811-A Organic compound and the Organic Light Emitting Diode using the organic compound 乐金显示有限公司 2017-07-28 CN disclosed
US-9608210-B2 Organic compound and organic light emitting diode using the same LG DISPLAY CO., LTD. (KR) 2017-03-28 US disclosed
US-9590191-B2 Organic compound and organic light emitting diode using the same LG DISPLAY CO., LTD. (KR) 2017-03-07 US disclosed
US-20160155957-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG DISPLAY CO., LTD. (KR) 2016-06-02 US disclosed
US-20160155956-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG DISPLAY CO., LTD. (KR) 2016-06-02 US disclosed
US-9281482-B2 Organic compound and organic light emitting diode using the same LG DISPLAY CO., LTD. (KR) 2016-03-08 US disclosed
US-20150162537-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG DISPLAY CO., LTD. (KR) 2015-06-11 US disclosed
EP-2881446-A2 Organic compound and organic light emitting diode using the same LG Display Co., Ltd. (KR) 2015-06-10 EP disclosed
CN-104693105-A Organic compound and organic light emitting diode using the same LG DISPLAY CO LTD 2015-06-10 CN disclosed
US-20130112948-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-05-09 US disclosed
US-20130112948-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-05-09 US disclosed
US-20060061265-A1 Aromatic amine derivative and organic electroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2006-03-23 US disclosed
EP-1559706-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130112948-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME CYP1B1, CYP1A1, CRY1 MEN1 1924/4885KMT2A 1868/4885RXFP1 761/4885
US-20060061265-A1 Aromatic amine derivative and organic electroluminescent element employing the same LUC7L2, ARL1, ASH2L MEN1 1381/4885KMT2A 727/4885RXFP1 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.