SCHEMBL127264

SCHEMBL127264

Brc1ccc(N(c2ccc(N(c3cc4ccccc4c4ccccc34)c3cc4ccccc4c4ccccc34)cc2)c2cc3ccccc3c3ccccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
TRPM4 Q8TD43 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 3/20 0.36
HIF1A Q16665 2/20 0.36
CYP1B1 Q16678 1/20 0.36
CYP2A6 P11509 2/20 0.35
HPRT1 P00492 3/20 0.34
TSHR P16473 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
RAD52 P43351 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
MAOB P27338 1/20 0.31
ERBB2 P04626 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5957022 0.98 TRPM4 (0.38) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL5956958 0.95 MEN1 (0.40) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL29993540 0.91 ALDH1A1 (0.46) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL5957001 0.91 CYP2A6 (0.43) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL17740549 0.91 ALDH1A1 (0.41) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL12476233 0.91 ALDH1A1 (0.46) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL17165568 0.91 ALDH1A1 (0.46) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL5957030 0.91 ALDH1A1 (0.36) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL29332853 0.89 CES2 (0.35) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL12012670 0.87 TRPM4 (0.41) MEN1KMT2ATRPM4ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1027 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-12029108-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-02 US disclosed
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-20110001134-A1 COMPOSITION FOR CHARGE-TRANSPORTING FILM AND ION COMPOUND, CHARGE-TRANSPORTING FILM AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME, AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PRODUCING CHARGE-TRANSPORTING FILM MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-06 US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION 2010-03-25 US disclosed
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION 2010-03-25 US disclosed
US-20070207341-A1 Composition For Charge-Transporting Film And Ion Compound, Charge-Transporting Film And Organic Electroluminescent Device Using Same, And Method For Manufacturing Organic Electroluminescent Device And Method For Producing Charge-Transporting Film MITSUBISHI CHEMICAL CORPORATION (JP) 2007-09-06 US disclosed
US-20070207341-A1 Composition For Charge-Transporting Film And Ion Compound, Charge-Transporting Film And Organic Electroluminescent Device Using Same, And Method For Manufacturing Organic Electroluminescent Device And Method For Producing Charge-Transporting Film MITSUBISHI CHEMICAL CORPORATION (JP) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029108-B2 Organic electroluminescent materials and devices LBR, DBF4, DNMT3A MEN1 3288/4885KMT2A 1873/4885RXFP1 374/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND MEN1 3990/4885KMT2A 3523/4885RXFP1 2814/4885
US-20100141127-A1 PHOSPHORESCENT EMITTERS PAICS, TYMP, NUDT1 MEN1 2832/4885KMT2A 2445/4885RXFP1 4756/4885
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, SBDS, OCIAD2 MEN1 4468/4885KMT2A 3905/4885RXFP1 4431/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 MEN1 2780/4885KMT2A 4273/4885RXFP1 4435/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP MEN1 4145/4885KMT2A 4312/4885RXFP1 2847/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG MEN1 3094/4885KMT2A 3450/4885RXFP1 4410/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 MEN1 2962/4885KMT2A 4442/4885RXFP1 3846/4885
US-11917902-B2 Organic electroluminescent materials and devices SOD1, NDUFV1, L1CAM MEN1 933/4885KMT2A 3691/4885RXFP1 4694/4885
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES SCLY, BZW2, GPX4 MEN1 2669/4885KMT2A 2845/4885RXFP1 4863/4885
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 MEN1 1427/4885KMT2A 816/4885RXFP1 4872/4885
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX DDT, ICOSLG, PDCD1LG2 MEN1 2576/4885KMT2A 3227/4885RXFP1 4597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.