SCHEMBL5957022

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL127264	0.98	MEN1 (0.37)	TRPM4MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL5956958	0.93	MEN1 (0.40)	TRPM4MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL5957030	0.92	ALDH1A1 (0.36)	TRPM4MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL5957001	0.89	CYP2A6 (0.43)	TRPM4MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL17165568	0.89	ALDH1A1 (0.46)	TRPM4MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL29993540	0.89	ALDH1A1 (0.46)	TRPM4MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL12476233	0.89	ALDH1A1 (0.46)	TRPM4MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL17740549	0.89	ALDH1A1 (0.41)	TRPM4MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL29332853	0.88	CES2 (0.35)	TRPM4MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL12012670	0.85	TRPM4 (0.41)	TRPM4MEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.