Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 15/20 | 1.00 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5957690 | 1.00 | TRPA1 (1.00) | TRPA1SCDALDH1A1MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL5957611 | 0.99 | TRPA1 (0.98) | TRPA1SCDALDH1A1MAPK1LMNA | |
| SCHEMBL5957632 | 0.94 | TRPA1 (1.00) | TRPA1BRD4 | |
| SCHEMBL5957620 | 0.91 | TRPA1 (0.84) | TRPA1 | |
| Hydrochloric Acid SCHEMBL5957848 | 0.91 | TRPA1 (0.83) | TRPA1 | |
| SCHEMBL5957319 | 0.91 | TRPA1 (1.00) | TRPA1SCDALDH1A1MAPK1LMNA | |
| SCHEMBL5957359 | 0.90 | TRPA1 (1.00) | TRPA1MAPK1 | |
| Hydrochloric Acid SCHEMBL5957509 | 0.90 | TRPA1 (0.98) | TRPA1SCDALDH1A1MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL5957637 | 0.90 | TRPA1 (0.81) | TRPA1SCD | |
| Hydrochloric Acid SCHEMBL5957392 | 0.90 | TRPA1 (0.81) | TRPA1ALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060040957-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY | 2006-02-23 | — | — | US | claimed |
| US-20060040957-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040957-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | MMP13, MMP25, MMP15 | TRPA1 3405/4885SCD 3138/4885ALDH1A1 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.