Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133434 | 0.85 | — | — | |
| SCHEMBL5675346 | 0.74 | — | — | |
| SCHEMBL8645184 | 0.73 | TP53 (0.36) | — | |
| SCHEMBL11584582 | 0.70 | — | — | |
| SCHEMBL5608046 | 0.70 | CYP2C19 (0.33) | OPRM1 | |
| SCHEMBL2128532 | 0.68 | OPRM1 (0.36) | OPRM1 | |
| 1,4-Butanediol SCHEMBL11761054 | 0.67 | CYP4F2 (0.31) | — | |
| SCHEMBL7600518 | 0.67 | EP300 (0.31) | — | |
| SCHEMBL5697820 | 0.66 | — | — | |
| SCHEMBL13740855 | 0.65 | CYP2C19 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060105047-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2006-05-18 | — | — | US | disclosed |
| US-20050100579-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2005-05-12 | — | — | US | disclosed |
| US-6858218-B2 | Hydrogel from polysiloxane-containing urethane prepolymer, tris (trimethylsiloxy) silylpropyl methacrylate, and a hydrophilic comonomer | BAUSCH & LOMB INCORPORATED (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030157141-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2003-08-21 | — | — | US | disclosed |
| US-6596294-B2 | Oxygen permeability and superior physical properties, contact lenses | BAUSCH & LOMB INCORPORATED | 2003-07-22 | — | — | US | disclosed |
| US-20020037271-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED | 2002-03-28 | — | — | US | disclosed |
| US-6312706-B1 | ACRYLIC POLYMERS, COPOLYMERS AND POLYSILOXANE URETHANES | BAUSCH & LOMB INCORPORATED | 2001-11-06 | — | — | US | disclosed |
| CN-1056626-C | Method for preparing surface active random copolymer | BAUSCH & LOMB (US) | 2000-09-20 | — | — | CN | disclosed |
| CN-1048265-C | Surface modification of polymer objects | BAUSCH & LOMB (US) | 2000-01-12 | — | — | CN | disclosed |
| CN-1048021-C | Process for preparing surface active macromonomers | BAUSCH & LOMB (US) | 2000-01-05 | — | — | CN | disclosed |
| US-5135297-A | Immersing a contact lens in an aqueous dispersion of a polymerizable surfactant macromer, a crosslinker and a free radical catalyst and irradiating with UV light; wetting agents | BAUSCH & LOMB INCORPORATED (US) | 1992-08-04 | — | — | US | disclosed |
| US-5128434-A | Contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1992-07-07 | — | — | US | disclosed |
| CN-1061980-A | The control of hard segment size in the urethane forming process | BAUSCH & LOMB (US) | 1992-06-17 | — | — | CN | disclosed |
| CN-1061978-A | Surface active macromonomers | BAUSCH & LOMB (US) | 1992-06-17 | — | — | CN | disclosed |
| WO-1992009639-A2 | SURFACE-ACTIVE MACROMONOMERS | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992009650-A1 | SURFACE COATING OF POLYMER OBJECTS | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992009644-A1 | SURFACE MODIFICATION OF POLYMER OBJECTS | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |
| CN-1061785-A | The surface modification of polymer articles | BAUSCH & LOMB (US) | 1992-06-10 | — | — | CN | disclosed |
| CN-1061786-A | The surface coated of polymer articles | BAUSCH & LOMB (US) | 1992-06-10 | — | — | CN | disclosed |
| EP-0401990-A2 | Prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1990-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037271-A1 | Novel prepolymers useful in biomedical devices | TMEM63A, ECPAS, COL2A1 | SLC6A2 3838/4885SLC6A4 4309/4885OPRM1 1609/4885 |
| US-20060105047-A1 | Novel prepolymers useful in biomedical devices | TMEM63A, ECPAS, COL2A1 | SLC6A2 3838/4885SLC6A4 4309/4885OPRM1 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.