Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 7/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PKLR | P30613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960350 | 0.68 | ESR1 (0.34) | POLBKMT2A | |
| SCHEMBL29796402 | 0.68 | RECQL (0.56) | POLBKMT2A | |
| SCHEMBL14332339 | 0.66 | — | — | |
| SCHEMBL12721329 | 0.66 | — | — | |
| SCHEMBL3632921 | 0.66 | FGFR1 (0.42) | HTR2AHTR2C | |
| SCHEMBL29411862 | 0.66 | FGFR1 (0.42) | HTR2AHTR2C | |
| SCHEMBL14737592 | 0.64 | RPS6KA5 (0.39) | KMT2A | |
| SCHEMBL1113576 | 0.63 | TP53 (0.35) | PKM | |
| SCHEMBL10049570 | 0.63 | KMO (0.44) | HTR2AHTR2CPOLB | |
| SCHEMBL26206533 | 0.61 | GPR139 (0.53) | GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682553-A1 | THIENOPYRAZOLES | Aventis Pharmaceuticals Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005026175-A1 | THIENOPYRAZOLES | AVENTIS PHARMACEUTICALS INC. (US) | 2005-03-24 | — | — | WO | disclosed |