Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170398 | 0.80 | L3MBTL1 (0.80) | L3MBTL1NPC1MAPTMEN1KMT2A | |
| SCHEMBL4507867 | 0.77 | MMP9 (0.69) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1886477 | 0.76 | NPC1 (0.80) | L3MBTL1NPC1MAPTMEN1KMT2A | |
| SCHEMBL7166063 | 0.74 | NPC1 (0.69) | L3MBTL1NPC1MAPTMEN1KMT2A | |
| SCHEMBL17128088 | 0.70 | MAPT (0.67) | L3MBTL1NPC1MAPTMEN1KMT2A | |
| SCHEMBL838060 | 0.69 | RAB9A (0.58) | L3MBTL1NPC1MAPTMEN1KMT2A | |
| SCHEMBL15096814 | 0.68 | NPC1 (0.55) | L3MBTL1NPC1MAPTMEN1KMT2A | |
| SCHEMBL347317 | 0.68 | SMN1; SMN2 (0.52) | L3MBTL1NPC1MAPTMEN1KMT2A | |
| SCHEMBL347316 | 0.68 | SMN1; SMN2 (0.52) | L3MBTL1NPC1MAPTMEN1KMT2A | |
| SCHEMBL31122061 | 0.67 | MAPK1 (0.50) | L3MBTL1NPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709019-A2 | THIAZOLE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005068444-A2 | THIAZOLE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-07-28 | — | — | WO | disclosed |