Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993397 | 0.80 | CES1 (0.46) | ALOX15TSHRCES2CES1SRD5A2 | |
| SCHEMBL28464639 | 0.79 | ALDH1A1 (0.52) | CES2CES1SRD5A2GSK3BALDH1A1 | |
| SCHEMBL3140047 | 0.79 | CES2 (0.48) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL17801512 | 0.78 | SMN1; SMN2 (0.50) | ERCC5FEN1GSK3BMAPK1ALDH1A1 | |
| SCHEMBL926435 | 0.77 | HPGD (0.44) | ALOX15TSHRCES2CES1CA1 | |
| SCHEMBL28400743 | 0.75 | CA1 (0.57) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL28590990 | 0.75 | CA2 (0.50) | CA1CA2GSK3BALDH1A1MAPT | |
| SCHEMBL2162369 | 0.75 | CES2 (0.53) | TSHRCES2CES1SRD5A2GSK3B | |
| SCHEMBL28783011 | 0.73 | SMN1; SMN2 (0.49) | TSHRCES2CES1ALDH1A1MAPT | |
| SCHEMBL28464681 | 0.73 | MEN1 (0.44) | ALOX15TSHRCES2CES1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808003-A | Preparation method of thioether | 甘肃农业大学 | 2020-10-23 | — | — | CN | disclosed |
| US-7109343-B2 | Metal catalysts and methods for making and using same | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2006-09-19 | — | — | US | disclosed |
| US-20050010049-A1 | Metal catalysts and methods for making and using same | DAVIES HUW M L (US) | 2005-01-13 | — | — | US | disclosed |
| US-6762304-B2 | BIS-TRANSITION METAL CATALYSTS HAVING D2 SYMMETRY | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2004-07-13 | — | — | US | disclosed |
| EP-1173278-B1 | METAL CATALYSTS AND METHODS FOR MAKING AND USING SAME | RES FOUNDATION OFSTATE UNIVERS (US) | 2004-06-30 | — | — | EP | disclosed |
| US-20020183535-A1 | Metal catalysts and methods for making and using same | DAVIES HUW M L (US) | 2002-12-05 | — | — | US | disclosed |
| US-6410746-B1 | ORGANOMETALLIC COMPOUND CONTAINING TRANSITION METAL | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | 2002-06-25 | — | — | US | disclosed |
| EP-1173278-A1 | METAL CATALYSTS AND METHODS FOR MAKING AND USING SAME | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064583-A1 | METAL CATALYSTS AND METHODS FOR MAKING AND USING SAME | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183535-A1 | Metal catalysts and methods for making and using same | COMT, SLC6A3, SLC6A2 | ALOX15 3759/4885TSHR 101/4885CES2 104/4885 |
| US-20050010049-A1 | Metal catalysts and methods for making and using same | SLC6A3, COMT, DRD4 | ALOX15 4432/4885TSHR 112/4885CES2 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.