Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25430781 | 0.86 | ALDH1A1 (0.44) | HTTMAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL3918092 | 0.81 | ALDH1A1 (0.41) | HTTMAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL28738770 | 0.79 | MAPT (0.47) | HTTMAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL11265555 | 0.77 | ALDH1A1 (0.38) | HTTKMT2ATSHRALDH1A1CYP1A2 | |
| SCHEMBL8680769 | 0.74 | MAPT (0.48) | HTTMAPTKMT2ATSHRCYP1A2 | |
| SCHEMBL29113996 | 0.74 | TSHR (0.39) | HTTMAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL3073772 | 0.74 | HTT (0.58) | HTTMAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL7110139 | 0.74 | MMP1 (0.45) | — | |
| SCHEMBL7123831 | 0.73 | TSHR (0.48) | HTTTSHRALDH1A1KCNN4AKT1 | |
| SCHEMBL10879317 | 0.72 | MAPT (0.47) | HTTMAPTKMT2ATSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028337-B1 | PROCESS FOR PREPARING MIXTURES OF DIPHENYLMETHANE DIISOCYANATES AND POLYPHENYL-POLYMETHYLENE POLYISOCYANATES | BASF Aktiengesellschaft (DE) | 1985-02-13 | — | — | EP | claimed |
| US-7022871-B2 | Process for the synthesis of polycarbamates | HUNTSMAN INTERNATIONAL LLC (US) | 2006-04-04 | — | — | US | disclosed |
| EP-1242368-B1 | PROCESS FOR THE SYNTHESIS OF POLYCARBAMATES | HUNTSMAN INT LLC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-20030135009-A1 | Process for the synthesis of polycarbamates | HUNTSMAN INTERNATIONAL LLC | 2003-07-17 | — | — | US | disclosed |
| EP-1242368-A2 | PROCESS FOR THE SYNTHESIS OF POLYCARBAMATES | HUNTSMAN INTERNATIONAL LLC (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001047871-A2 | PROCESS FOR THE SYNTHESIS OF POLYCARBAMATES | HUNTSMAN INTERNATIONAL LLC (US) | 2001-07-05 | — | — | WO | disclosed |
| US-4349484-A | Process for the manufacture of mixtures of diphenylmethane diisocyanates and polyphenyl polymethylene polyisocyanates | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135009-A1 | Process for the synthesis of polycarbamates | ODC1, UROD, PUF60 | HTT 2648/4885MAPT 2578/4885KMT2A 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.