Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005490 | 0.81 | HTT (0.55) | HTTALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL6139504 | 0.76 | TSHR (0.50) | HTTALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL3083611 | 0.75 | KMT2A (0.43) | HTTTSHRKMT2AMEN1MAPT | |
| SCHEMBL5962490 | 0.74 | HTT (0.46) | HTTALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7167864 | 0.74 | HTT (0.69) | HTTALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL251792 | 0.73 | ALDH1A1 (0.47) | HTTALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL27830529 | 0.72 | HTT (0.45) | HTTALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL27696956 | 0.72 | KIF11 (0.40) | HTTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL1908316 | 0.72 | ALDH1A1 (0.65) | HTTALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL3613086 | 0.72 | ALDH1A1 (0.65) | HTTALDH1A1TSHRKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101535305-B | 5-hydroxymethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD | 2013-09-18 | — | — | CN | disclosed |
| US-7795166-B2 | Functional group-selective hydrogenation catalyst and functional group-selective hydrogenation method | N.E. CHEMCAT CORPORATION (JP) | 2010-09-14 | — | — | US | disclosed |
| CN-101535305-A | 5-hydroxymethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-16 | — | — | CN | disclosed |
| US-20070155617-A1 | FUNCTIONAL GROUP-SELECTIVE HYDROGENATION CATALYST AND FUNCTIONAL GROUP-SELECTIVE HYDROGENATION METHOD | N. E. CHEMCAT CORPORATION (JP) | 2007-07-05 | — | — | US | disclosed |