Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1710167 | 0.80 | LMNA (0.59) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL12633216 | 0.80 | LMNA (0.59) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL1870853 | 0.80 | LMNA (0.59) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL15434262 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL27830937 | 0.80 | NFE2L2 (0.48) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL8925959 | 0.77 | KDM4E (0.45) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL20034048 | 0.77 | KDM4E (0.45) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL463783 | 0.76 | LMNA (0.57) | ALDH1A1LMNAHPGDMAPTMEN1 | |
| SCHEMBL30332152 | 0.76 | LMNA (0.57) | ALDH1A1LMNAHPGDMAPTMEN1 | |
| SCHEMBL16307970 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041649-B2 | Method for treating neurological conditions and inducing immunosuppression with cephaibols | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-05-09 | — | — | US | disclosed |