Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 3/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5965964 | 0.90 | FKBP1A (0.39) | FKBP1AACEDPP4DPP8 | |
| SCHEMBL5966055 | 0.85 | FKBP1A (0.49) | FKBP1A | |
| SCHEMBL5966154 | 0.77 | FKBP1A (0.45) | FKBP1A | |
| SCHEMBL7940809 | 0.76 | FKBP1A (0.44) | FKBP1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL5966088 | 0.72 | FKBP1A (0.60) | FKBP1AACE | |
| SCHEMBL5966105 | 0.70 | FKBP1A (0.39) | FKBP1AACEDPP4DPP8KCNK3 | |
| SCHEMBL7426919 | 0.70 | FKBP1A (0.53) | FKBP1AKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL7469127 | 0.68 | FKBP1A (0.42) | FKBP1AACEKDM4EALDH1A1 | |
| SCHEMBL5700583 | 0.67 | FKBP1A (0.53) | FKBP1A | |
| SCHEMBL8552264 | 0.65 | ALDH1A1 (0.57) | FKBP1AACEALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227859-B1 | NEUROPHILIN LIGANDS FOR TREATING OCULAR CONDITIONS | ALCON INC (CH) | 2006-08-09 | — | — | EP | claimed |
| EP-0777478-B1 | INHIBITORS OF ROTAMASE ENZYME ACTIVITY | GUILFORD PHARM INC (US) | 2001-11-07 | — | — | EP | claimed |