Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.55 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148908 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL5966137 | 0.95 | FKBP1A (0.57) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL5966186 | 0.95 | FKBP1A (0.57) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL5966141 | 0.95 | FKBP1A (0.57) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL14407796 | 0.94 | FKBP1A (0.56) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL7247533 | 0.90 | FKBP1A (0.45) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL14407859 | 0.86 | ALOX5 (0.54) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL6079299 | 0.84 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL14407821 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL13230 | 0.83 | CA2 (0.67) | ALDH1A1SMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |