SCHEMBL5966413

SCHEMBL5966413

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.65
OPRD1 P41143 3/20 0.65
OPRK1 P41145 2/20 0.65
CTSB P07858 1/20 0.62
MME P08473 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5966405 1.00 OPRM1 (0.65) OPRM1OPRD1OPRK1CTSBMME
SCHEMBL31754371 0.95 OPRD1 (0.62) OPRM1OPRD1OPRK1CTSBMME
SCHEMBL29789592 0.95 CTSB (0.64) OPRM1OPRD1OPRK1CTSBMME
SCHEMBL29746506 0.95 OPRM1 (0.60) OPRM1OPRD1OPRK1CTSBMME
SCHEMBL9829182 0.92 MME (0.64) OPRM1OPRD1OPRK1MME
SCHEMBL9551455 0.92 MME (0.64) OPRM1OPRD1OPRK1MME
SCHEMBL5370772 0.92 MME (0.64) OPRM1OPRD1OPRK1MME
SCHEMBL8983313 0.91 CTSB (0.62) OPRM1OPRD1OPRK1CTSBMME
SCHEMBL8983297 0.91 CTSB (0.62) OPRM1OPRD1OPRK1CTSBMME
SCHEMBL23142822 0.91 CTSB (0.55) OPRM1OPRD1OPRK1CTSBMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682156-A1 LINKER AND DRUG CONJUGATE USING SAME, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF Shanghai Affinity Biopharmaceutical Co., Ltd. (CN) 2026-01-21 EP disclosed
CN-118666946-A Connector, coupling drug using same, antibody coupling drug and application of antibody coupling drug 上海亲合力生物医药科技股份有限公司 2024-09-20 CN disclosed
WO-2024188314-A1 LINKER AND DRUG CONJUGATE USING SAME, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF 上海亲合力生物医药科技股份有限公司 2024-09-19 WO disclosed
CN-220176828-U Microchannel reaction device for synthesizing polypeptide 厦门胜泽泰医药科技有限公司 2023-12-15 CN disclosed
CN-116589531-A Microchannel reaction device for synthesizing polypeptide and leucine enkephalin cyclic synthesis process 厦门胜泽泰医药科技有限公司 2023-08-15 CN disclosed
CN-115747058-A Micro-fluidic chip, detection system and surface treatment reagent combination therein 上海柏慧康生物科技有限公司 2023-03-07 CN disclosed
US-7560286-B2 Mass spectrometric method for structural analysis of chain nitrogen-containing compounds using sqauric acid SUNTORY HOLDINGS LIMITED (JP) 2009-07-14 US disclosed
US-7560286-B2 Mass spectrometric method for structural analysis of chain nitrogen-containing compounds using sqauric acid SUNTORY HOLDINGS LIMITED (JP) 2009-07-14 US disclosed
US-20060275900-A1 Methods for in vitro expansion and transdifferentiation of human pancreatic acinar cells into insulin-producing cells BECTON, DICKINSON AND COMPANY (US) 2006-12-07 US disclosed
US-20060122104-A1 Methods for in vitro expansion and transdifferentiation of human pancreatic acinar cells into insulin-producing cells BECTON, DICKINSON AND COMPANY 2006-06-08 US disclosed
EP-0804246-B1 DRUG DELIVERY AGENTS INCORPORATING MITOMYCIN EUROP ECONOMIC COMMUNITY (LU) 2000-05-17 EP disclosed
EP-0804246-A1 DRUG DELIVERY AGENTS INCORPORATING MITOMYCIN Commission of the European Communities (LU) 1997-11-05 EP disclosed
EP-0432022-B1 Medium for reaction and dissolution of peptides and process of peptide synthesis by making use of said medium RHONE POULENC CHIMIE (FR) 1996-10-23 EP disclosed
WO-1995005200-A1 DRUG DELIVERY AGENTS INCORPORATING MITOMYCIN EUROPEAN COMMUNITY (LU) 1995-02-23 WO disclosed
EP-0421848-B1 Process to stabilise peptides and process to synthetise peptides RHONE POULENC CHIMIE (FR) 1995-02-08 EP disclosed
EP-0432022-A1 Medium for reaction and dissolution of peptides and process of peptide synthesis by making use of said medium RHONE-POULENC CHIMIE (FR) 1991-06-12 EP disclosed
EP-0421848-A1 Process to stabilise peptides and process to synthetise peptides RHONE-POULENC CHIMIE (FR) 1991-04-10 EP disclosed