Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 9/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.81 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.81 |
| ▸ | AHCY | P23526 | 2/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889873 | 0.90 | ADORA2B (0.81) | ADORA2AADORA2BADORA3ADORA1AHCY | |
| SCHEMBL13382546 | 0.84 | AHCY (0.74) | ADORA2AADORA2BADORA3ADORA1AHCY | |
| SCHEMBL9155975 | 0.83 | AHCY (0.76) | ADORA2AADORA2BADORA3ADORA1AHCY | |
| SCHEMBL30555907 | 0.83 | AHCY (0.76) | ADORA2AADORA2BADORA3ADORA1AHCY | |
| SCHEMBL9155960 | 0.83 | AHCY (0.76) | ADORA2AADORA2BADORA3ADORA1AHCY | |
| SCHEMBL15250732 | 0.83 | ADORA3 (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL19532413 | 0.83 | ADORA3 (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6481597 | 0.82 | ADORA3 (1.00) | ADORA2AADORA2BADORA3ADORA1AHCY | |
| 5'-Carboxy Adenosine SCHEMBL2117314 | 0.82 | AHCY (1.00) | ADORA2AADORA2BADORA3ADORA1AHCY | |
| 5'-Carboxy Adenosine SCHEMBL2117257 | 0.82 | AHCY (1.00) | ADORA2AADORA2BADORA3ADORA1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636359-A4 | METHODS FOR TREATING PAIN | UNIV COLORADO REGENTS (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1636359-A2 | METHODS FOR TREATING PAIN | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2006-03-22 | — | — | EP | disclosed |
| WO-2005000215-A2 | METHODS FOR TREATING PAIN | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2005-01-06 | — | — | WO | disclosed |