Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.60 |
| ▸ | CTSS | P25774 | 4/20 | 0.60 |
| ▸ | CTSK | P43235 | 6/20 | 0.59 |
| ▸ | CTSB | P07858 | 5/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | CASP9 | P55211 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13888701 | 1.00 | CTSL (0.60) | CTSLCTSSCTSKCTSBCASP3 | |
| SCHEMBL12588646 | 0.97 | CASP3 (0.59) | CTSLCTSSCTSKCTSBCASP3 | |
| SCHEMBL13888699 | 0.97 | CASP3 (0.59) | CTSLCTSSCTSKCTSBCASP3 | |
| SCHEMBL12588645 | 0.97 | CASP3 (0.59) | CTSLCTSSCTSKCTSBCASP3 | |
| SCHEMBL5967873 | 0.91 | ECE1 (0.55) | CTSLCTSSCTSKCTSBCASP3 | |
| SCHEMBL25693730 | 0.90 | CTSS (0.73) | CTSLCTSSCTSKCTSBMEN1 | |
| SCHEMBL19557810 | 0.89 | CASP3 (0.61) | CTSLCTSSCTSKCTSBCASP3 | |
| SCHEMBL10453618 | 0.89 | CASP3 (0.61) | CTSLCTSSCTSKCTSBCASP3 | |
| SCHEMBL8658774 | 0.88 | MEN1 (0.74) | CTSLCTSSCTSKCTSBCASP3 | |
| SCHEMBL13888698 | 0.88 | MEN1 (0.74) | CTSLCTSSCTSKCTSBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178299-A1 | PRODRUGS OF GANAXOLONE | MARINUS PHARMACEUTICALS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023118961-A1 | ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF | INTOCELL, INC. (KR) | 2023-06-29 | — | — | WO | disclosed |
| EP-1647545-A1 | Antiviral protease inhibitors | MEDIVIR AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| EP-1005493-B1 | ANTIVIRAL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2005-11-02 | — | — | EP | disclosed |
| US-6489364-B2 | FROM L-MANNONIC-GAMMA-LACTONE INTERMEDIATES; FOR PROPHYLAXIS OF HIV/AIDS HIV | MEDIVIR AB (SE) | 2002-12-03 | — | — | US | disclosed |
| US-6291687-B1 | USED ASPARTYL PROTEASE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) | MEDIVIR AB (SE) | 2001-09-18 | — | — | US | disclosed |
| EP-1005493-A1 | ANTIVIRAL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2000-06-07 | — | — | EP | disclosed |
| WO-1998045330-A1 | ANTIVIRAL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 1998-10-15 | — | — | WO | disclosed |