Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CTSL | P07711 | 3/20 | 0.74 |
| ▸ | CTSS | P25774 | 3/20 | 0.74 |
| ▸ | CTSB | P07858 | 3/20 | 0.74 |
| ▸ | CTSK | P43235 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 2/20 | 0.61 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13888698 | 1.00 | MEN1 (0.74) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL13888695 | 0.97 | MEN1 (0.71) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL2446560 | 0.88 | CTSL (0.80) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL7049933 | 0.88 | CTSB (0.72) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL24734375 | 0.88 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL5145628 | 0.88 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL8837339 | 0.88 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL8837344 | 0.88 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL13888701 | 0.88 | CTSL (0.60) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL221434 | 0.88 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763631-A | CIS-EPOXIDE COMPOUNDS; ANTIVIRUS AGENTS; USEFUL TO TREAT THE AIDS | LUCKY LIMITED (KR) | 1998-06-09 | — | — | US | disclosed |
| US-5744621-A | CIS-EPOXIDE COMPOUNDS | LUCKY LIMITED. (KR) | 1998-04-28 | — | — | US | disclosed |
| EP-0601486-B1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD (KR) | 1997-10-29 | — | — | EP | disclosed |
| US-5587388-A | AIDS; VIRICIDES | LUCKY LIMITED (KR) | 1996-12-24 | — | — | US | disclosed |
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | disclosed |