SCHEMBL5969705

SCHEMBL5969705

C=CC(=O)CC(=O)CC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TSHR P16473 4/20 0.42
ALDH1A1 P00352 4/20 0.42
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 1/20 0.32
BACE1 P56817 1/20 0.31
FGFR4 P22455 1/20 0.30
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL415833 0.86
Hydroxyamine SCHEMBL28262455 0.81 ALOX15 (0.46) ALOX15HSD17B10TSHRALDH1A1LDHA
SCHEMBL290398 0.80
SCHEMBL4816091 0.77 ALDH1A1 (0.46) TSHRALDH1A1LMNAMAPK1TDP1
SCHEMBL9277936 0.77 HSD17B10 (0.48) ALOX15HSD17B10TSHRALDH1A1LDHA
SCHEMBL2184678 0.76 LDHA (0.67) ALOX15HSD17B10TSHRALDH1A1LDHA
SCHEMBL28522 0.76 LDHA (0.67) ALOX15HSD17B10TSHRALDH1A1LDHA
SCHEMBL7745095 0.76 LDHA (0.42) ALOX15HSD17B10TSHRALDH1A1LDHA
SCHEMBL306505 0.74
SCHEMBL320091 0.73 LDHA (0.61) ALOX15HSD17B10TSHRALDH1A1LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705837-B1 Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES (JP) 2002-08-07 EP claimed
US-5677455-A Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES, LTD. (JP) 1997-10-14 US claimed
EP-0705837-A2 Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES, LTD. (JP) 1996-04-10 EP claimed
JP-8127557-A None JP disclosed
CN-106661390-B Maleimide membranes 古河电气工业株式会社 2020-08-07 CN disclosed
EP-1481802-B1 Directly imageable planographic printing plate precursor and a method of producing planographic printing plate TORAY INDUSTRIES (JP) 2006-09-20 EP disclosed
EP-0914942-B1 Directly imageable waterless planographic printing plate precursor and a method of producing planographic printing plates TORAY INDUSTRIES (JP) 2005-05-25 EP disclosed
EP-1481802-A1 Directly imageable planographic printing plate precursor and a method of producing planographic printing plate TORAY INDUSTRIES, INC. (JP) 2004-12-01 EP disclosed
US-6777156-B1 HIGH SENSITIVITY AND HIGH IMAGE REPRODUCIBILITY; EASILY MADE WITHOUT WATER TORAY INDUSTRIES, INC. (JP) 2004-08-17 US disclosed
US-20030228540-A1 Heat sensitive elements; organometallic compound TORAY INDUSTRIES, INC. (JP) 2003-12-11 US disclosed
JP-2003137870-A METHOD FOR PRODUCING 3,5-DIOXO-6-HEPTENOIC ACID DERIVATIVES, AND INTERMEDIATE THEREFOR NISSAN CHEM IND LTD 2003-05-14 JP disclosed
US-5744604-A Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES, LTD. (JP) 1998-04-28 US disclosed
US-5677455-A Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES, LTD. (JP) 1997-10-14 US disclosed
US-5677455-A Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES, LTD. (JP) 1997-10-14 US disclosed
US-5677455-A Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES, LTD. (JP) 1997-10-14 US disclosed
JP-H08127557-A PRODUCTION OF 3-OXY-5-OXO-6-HEPTENOIC ACID DERIVATIVE UBE IND LTD 1996-05-21 JP disclosed
EP-0705837-A2 Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES, LTD. (JP) 1996-04-10 EP disclosed
EP-0705837-A2 Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES, LTD. (JP) 1996-04-10 EP disclosed
EP-0705837-A2 Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives UBE INDUSTRIES, LTD. (JP) 1996-04-10 EP disclosed
EP-0013376-B1 ISOXAZOLE DERIVATIVE, PROCESS FOR ITS PREPARATION AND COMPOSITION CONTAINING IT HOECHST AKTIENGESELLSCHAFT (DE) 1982-05-19 EP disclosed