Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 5/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL4963388 | 0.95 | GAA (0.53) | GAACTBP2EGFRERBB2CA1 | |
| SCHEMBL31664355 | 0.95 | GAA (0.53) | GAACTBP2EGFRERBB2CA1 | |
| SCHEMBL30363672 | 0.95 | CA1 (0.54) | GAACTBP2EGFRERBB2CA1 | |
| SCHEMBL11578280 | 0.95 | GAA (0.53) | GAACTBP2EGFRERBB2CA1 | |
| SCHEMBL14813077 | 0.82 | CA1 (0.50) | GAACTBP2EGFRERBB2CA1 | |
| SCHEMBL4962898 | 0.81 | ALDH1A1 (0.49) | GAACTBP2EGFRERBB2POLB | |
| SCHEMBL526194 | 0.80 | GAA (0.57) | GAACTBP2EGFRERBB2TDP1 | |
| SCHEMBL3871526 | 0.79 | CTBP2 (0.60) | GAACTBP2EGFRERBB2TDP1 | |
| SCHEMBL11185173 | 0.78 | GAA (0.55) | GAACTBP2EGFRERBB2TDP1 | |
| SCHEMBL104746 | 0.78 | CA2 (0.62) | GAACTBP2EGFRERBB2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128608-A1 | Novel chemical compounds and their use | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128608-A1 | Novel chemical compounds and their use | PGLS, ABCG2, UGCG | GAA 241/4885CTBP2 4117/4885EGFR 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.