Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969950 | 0.87 | SLC6A2 (0.59) | SLC6A2SLC6A3POLBCHRNA7HTR3E | |
| SCHEMBL30291012 | 0.79 | ALDH1A1 (0.34) | SLC6A2SLC6A3POLBCHRNA7SLC6A4 | |
| SCHEMBL22195189 | 0.76 | THRB (0.38) | SLC6A2SLC6A3POLBCHRNA7HTR3E | |
| SCHEMBL4364782 | 0.75 | CYP19A1 (0.42) | MEN1KMT2AHSD17B10 | |
| SCHEMBL8308445 | 0.75 | IDO1 (0.58) | CHRM4HSD17B10TSHR | |
| SCHEMBL18817861 | 0.72 | IDO1 (0.60) | SMN1; SMN2MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL29829637 | 0.72 | POLB (0.50) | POLBCHRM4SMN1; SMN2TSHR | |
| SCHEMBL24988700 | 0.70 | ALDH1A1 (0.40) | POLBCHRM3CHRM1CHRM2CYP2D6 | |
| SCHEMBL8425500 | 0.70 | ALDH1A1 (0.60) | LMNASMN1; SMN2HSD17B10TSHR | |
| SCHEMBL7596802 | 0.70 | POLB (0.52) | POLBEDNRALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565421-B1 | A METHOD FOR PREPARING INDAN-1,3-DICARBOXYLIC ACID | PFIZER PROD INC (US) | 2008-07-23 | — | — | EP | claimed |