SCHEMBL597189

SCHEMBL597189

CO[SiH2]OC.c1ccc(N2CC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRNA7 P36544 3/20 0.53
▸ ALDH1A1 P00352 4/20 0.50
▸ MAPT P10636 3/20 0.50
▸ SIGMAR1 Q99720 2/20 0.50
▸ DRD2 P14416 2/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ CHRNB2 P17787 1/20 0.50
▸ NFKB1 P19838 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ CHRNA3 P32297 1/20 0.50
▸ CHRNA4 P43681 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ HTT P42858 1/20 0.50
▸ LMNA P02545 2/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ POLB P06746 1/20 0.48
▸ APOBEC3A P31941 1/20 0.48
▸ PMP22 Q01453 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL164538 0.81 LMNA (0.67) CHRNA7ALDH1A1MAPTSIGMAR1DRD2
SCHEMBL576814 0.81 LMNA (0.67) CHRNA7ALDH1A1MAPTSIGMAR1DRD2
SCHEMBL16924853 0.81 LMNA (0.67) CHRNA7ALDH1A1MAPTSIGMAR1DRD2
SCHEMBL385012 0.81 — —
SCHEMBL576454 0.81 LMNA (0.67) CHRNA7ALDH1A1MAPTSIGMAR1DRD2
SCHEMBL2115191 0.78 CHRNA7 (0.53) CHRNA7ALDH1A1MAPTSIGMAR1DRD2
SCHEMBL7258870 0.78 LMNA (0.64) CHRNA7ALDH1A1MAPTSIGMAR1DRD2
SCHEMBL15361051 0.78 CHRNA7 (0.58) CHRNA7ALDH1A1MAPTSIGMAR1DRD2
SCHEMBL6153220 0.77 ALDH1A1 (0.66) ALDH1A1MAPTSIGMAR1DRD2MAPK1
Hydrochloric Acid SCHEMBL11552188 0.77 CHRNA7 (0.52) CHRNA7ALDH1A1MAPTSIGMAR1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3328958-B1 USE OF A SINGLE OR MULTI COMPONENT SYSTEM FOR SECURING ANCHORING MEANS FISCHERWERKE GMBH & CO KG (DE) 2022-10-05 — — EP claimed
EP-3328959-B1 USE OF A SINGLE-COMPONENT SYSTEM FOR SECURING ANCHORING MEANS FISCHERWERKE GMBH & CO KG (DE) 2020-06-03 — — EP claimed
EP-3328958-B1 USE OF A SINGLE OR MULTI COMPONENT SYSTEM FOR SECURING ANCHORING MEANS FISCHERWERKE GMBH & CO KG (DE) 2022-10-05 — — EP disclosed
EP-3328959-A1 USE OF A SINGLE-COMPONENT SYSTEM FOR SECURING ANCHORING MEANS fischerwerke GmbH & Co. KG (DE) 2018-06-06 — — EP disclosed
US-9024051-B2 Organoxysilane compounds having silyl-protected secondary amino group and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-05 — — US disclosed
US-20130296593-A1 ORGANOXYSILANE COMPOUNDS HAVING SILYL-PROTECTED SECONDARY AMINO GROUP AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-11-07 — — US disclosed
EP-2660244-A1 Organoxysilane compounds having silyl-protected secondary amino group and making method Shin-Etsu Chemical Co., Ltd. (JP) 2013-11-06 — — EP disclosed
US-20120165493-A1 ISOCYANATE-FREE SILANE-CROSSLINKING COMPOUNDS WACKER CHEMIE AG (DE) 2012-06-28 — — US disclosed
US-8114233-B2 Method for adhesive bonding with foamable mixtures containing alkoxysilane-terminated prepolymers WACKER CHEMIE AG (DE) 2012-02-14 — — US disclosed
US-7875658-B2 Isocyanate-free prepolymer mixtures for producing noncracking spray foams and have improved fireproofing; a foamable polyetherurethane based on halogenated polyethers having alkoxysilane end groups and a blowing agent; shrinkage inhibition;nontoxic insulation; construction materials; seals WACKER CHEMIE AG (DE) 2011-01-25 — — US disclosed
US-20100324205-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2010-12-23 — — US disclosed
US-20090198000-A1 Liquid fluorine-containing and two-component compositions for the surface treatment of mineral and non-mineral substrates EVONIK DEGUSSA GMBH (DE) 2009-08-06 — — US disclosed
US-7550517-B2 Expandable mixtures that are devoid of isocyanates WACKER CHEMIE AG (DE) 2009-06-23 — — US disclosed
EP-1348747-B1 Gas barrier coating composition and method for manufacturing same JSR CORP (JP) 2007-02-14 — — EP disclosed
US-20060189705-A1 Expandable mixtures that are devoid of isocyanates WACKER CHEMIE AG (DE) 2006-08-24 — — US disclosed
US-20060148921-A1 Expansible mixtures devoid of isocyanates exhibiting improved fire behaviour WACKER CHEMIE AG (DE) 2006-07-06 — — US disclosed
US-20060084711-A1 Foaming mixtures WACKER CHEMIE AG (DE) 2006-04-20 — — US disclosed
US-20040072921-A1 Polyurethane modified with organosilicon compound WACKER CHEMIE AG (DE) 2004-04-15 — — US disclosed
US-20030187113-A1 Gas barrier coating composition and method for manufacturing same JSR CORPORATION (JP) 2003-10-02 — — US disclosed
EP-1348747-A1 Gas barrier coating composition and method for manufacturing same JSR Corporation (JP) 2003-10-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130296593-A1 ORGANOXYSILANE COMPOUNDS HAVING SILYL-PROTECTED SECONDARY AMINO GROUP AND MAKING METHOD AS3MT, SUGT1, PNMT CHRNA7 4589/4885ALDH1A1 2214/4885MAPT 231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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