Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119481 | 0.90 | RXRA (0.59) | TP53BCL2RXRARXRBCYP1A2 | |
| SCHEMBL3037130 | 0.87 | BCL2 (0.67) | TP53BCL2CYP1A2CYP2A6PTGS2 | |
| Water SCHEMBL9719807 | 0.85 | BCL2 (0.65) | TP53BCL2CYP1A2CYP2A6PTGS2 | |
| SCHEMBL29489424 | 0.83 | BCL2 (0.62) | TP53BCL2CYP1A2CYP2A6PTGS2 | |
| SCHEMBL5547358 | 0.83 | BCL2 (0.62) | TP53BCL2CYP1A2CYP2A6PTGS2 | |
| SCHEMBL27720523 | 0.82 | TP53 (0.46) | TP53BCL2RXRARXRBCYP1A2 | |
| SCHEMBL19259584 | 0.80 | RXRA (0.46) | TP53BCL2RXRARXRBCYP1A2 | |
| SCHEMBL91256 | 0.80 | RXRA (0.50) | TP53BCL2RXRARXRBPTGS2 | |
| SCHEMBL17954220 | 0.80 | RXRA (0.55) | TP53BCL2RXRARXRBPTGS2 | |
| SCHEMBL13226833 | 0.80 | RXRA (0.46) | TP53BCL2RXRARXRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1454931-B1 | PROPYLENE BLOCK COPOLYMER | JAPAN POLYPROPYLENE CORP (JP) | 2018-01-24 | — | — | EP | disclosed |
| EP-1520863-B1 | CATALYST FOR ALPHA-OLEFIN POLYMERISATION AND PROCESS FOR THE PRODUCTION OF ALPHA-OLEFIN POLYMER | JAPAN POLYPROPYLENE CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| EP-2009017-B1 | NOVEL TRANSITION METAL COMPOUND, CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING PROPYLENE/ETHYLENE-ALPHA -OLEFIN BLOCK COPOLYMER BY USING THE CATALYST | JAPAN POLYPROPYLENE CORP (JP) | 2013-06-26 | — | — | EP | disclosed |
| CN-101421286-B | Novel transition metal compound, catalyst for olefin polymerization containing the same, and method for producing propylene/ethylene-alpha-olefin block copolymer by using the catalyst | JAPAN POLYPROPYLENE CORP | 2013-04-24 | — | — | CN | disclosed |
| EP-1927628-B1 | PROPYLENE RESIN COMPOSITION | JAPAN POLYPROPYLENE CORP (JP) | 2012-09-12 | — | — | EP | disclosed |
| US-20120202766-A1 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-8114997-B2 | N4-acylcytosine nucleosides for treatment of viral infections | PHARMASSET, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-7915359-B2 | Propylene resin composition | JAPAN POLYPROPYLENE CORPORATION (JP) | 2011-03-29 | — | — | US | disclosed |
| CN-101273088-B | Propylene resin composition | JAPAN POLYPROPYLENE CORP | 2011-03-23 | — | — | CN | disclosed |
| US-7906599-B2 | Transition metal compound, catalyst for olefin polymerization containing the same, and method for producing propylene/ethylene-α-olefin block copolymer by using the catalyst | JAPAN POLYPROPYLENE CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| CN-1417236-A | Modified propylene polymer, composition containing the same and use thereof | MITSUBISHI CHEM IND (JP) | 2003-05-14 | — | — | CN | disclosed |
| EP-1308470-A2 | Modified propylene polymer, composition containing the same and use thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-20020045535-A1 | Catalysts for polymerization of alpha-olefins, process for producing alpha-olefin polymers, novel transition metal compounds and catalyst components for polymerization of alpha-olefin | MITSUBISHI CHEMICAL CORPORATION. | 2002-04-18 | — | — | US | disclosed |
| US-6344530-B2 | POLYMERIZATION CATALYST OF A TRANSITION METAL COMPOUND, AN ION EXCHANGEABLE LAYER OR AN INORGANIC SILICATE AND AN ORGANOALUMINUM COMPOUND | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-02-05 | — | — | US | disclosed |
| US-6340652-B1 | AS POLYMERIZATION CATALYST | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| US-20010034425-A1 | Process for producing alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION | 2001-10-25 | — | — | US | disclosed |
| US-6252097-B1 | Transition metal compounds | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-06-26 | — | — | US | disclosed |
| JP-2001048894-A | NEW TRANSITION METAL COMPOUND, OLEFIN POLYMERIZATION CATALYST COMPONENT AND PRODUCTION OF α-OLEFIN POLYMER | MITSUBISHI CHEMICALS CORP | 2001-02-20 | — | — | JP | disclosed |
| CN-1189506-A | Catalyst for polymerizing alpha-olefin, process for producing alpha-olefin polymer, novel transition metal compound for polymerizing alpha-olefin and catalyst component | MITSUBISHI CHEM CORP (JP) | 1998-08-05 | — | — | CN | disclosed |
| EP-0846696-A1 | Catalyst for polymerization of alpha-olefins | Mitsubishi Chemical Corporation (JP) | 1998-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202766-A1 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS | ENTPD5, DUT, NT5C3B | TP53 2565/4885BCL2 2263/4885RXRA 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.