Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 6/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2683501 | 0.77 | NSD2 (0.38) | KDM4ENSD2GAAPLCG1DNMT1 | |
| SCHEMBL596752 | 0.73 | ALDH1A1 (0.37) | KDM4ENPY1RALDH1A1HPGDALOX15 | |
| SCHEMBL7834223 | 0.68 | KDM4E (0.43) | KDM4EGAACASP6NPY1RALDH1A1 | |
| SCHEMBL7834227 | 0.68 | KDM4E (0.43) | KDM4EGAACASP6NPY1RALDH1A1 | |
| SCHEMBL8565246 | 0.68 | NSD2 (0.39) | KDM4ENSD2GAAPLCG1DNMT1 | |
| SCHEMBL6095568 | 0.68 | MEN1 (0.36) | KDM4EGAANPY1RNT5EALDH1A1 | |
| SCHEMBL6095575 | 0.68 | MEN1 (0.36) | KDM4EGAANPY1RNT5EALDH1A1 | |
| SCHEMBL8559187 | 0.65 | KDM4E (0.40) | KDM4EGAANPY1RALDH1A1HPGD | |
| SCHEMBL23718251 | 0.63 | KDM4E (0.38) | KDM4EGAACASP6NT5EALDH1A1 | |
| SCHEMBL8560999 | 0.63 | HTT (0.41) | KDM4ENSD2GAAPLCG1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115007-B2 | Synthesis of diaminodinitropyridine | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-14 | — | — | US | claimed |
| EP-2217570-A2 | SYNTHESIS OF DIAMINODINITROPYRIDINE AND DIAMINODINITROBENZENE | E. I. du Pont de Nemours and Company (US) | 2010-08-18 | — | — | EP | claimed |
| WO-2009070515-A2 | SYNTHESIS OF DIAMINODINITROPYRIDINE AND DIAMINODINITROBENZENE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-04 | — | — | WO | claimed |
| US-20090137814-A1 | Synthesis of diaminodinitropyridine | DUPONT SAFETY & CONSTRUCTION, INC. | 2009-05-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137814-A1 | Synthesis of diaminodinitropyridine | ODC1, NOS1, SRM | KDM4E 2615/4885NSD2 1321/4885GAA 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.