Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017759 | 1.00 | CTSB (0.49) | CTSBCTSSCTSKCTSLCYP3A4 | |
| SCHEMBL7442293 | 1.00 | CTSB (0.49) | CTSBCTSSCTSKCTSLCYP3A4 | |
| SCHEMBL8096746 | 0.98 | CYP3A4 (0.49) | CTSBCTSSCTSKCTSLCYP3A4 | |
| SCHEMBL8096744 | 0.98 | CYP3A4 (0.49) | CTSBCTSSCTSKCTSLCYP3A4 | |
| SCHEMBL7306189 | 0.92 | CYP2C19 (0.48) | CYP3A4CYP2C9CYP2C19ALDH1A1KMT2A | |
| SCHEMBL7306184 | 0.92 | CYP2C19 (0.48) | CYP3A4CYP2C9CYP2C19ALDH1A1KMT2A | |
| SCHEMBL6479809 | 0.84 | IDO1 (0.52) | CTSBCTSSCTSKCTSLCYP3A4 | |
| Hydrochloric Acid SCHEMBL7297833 | 0.83 | IDO1 (0.51) | CTSBCTSSCTSKCTSLCYP3A4 | |
| Hydrochloric Acid SCHEMBL3825774 | 0.83 | IDO1 (0.51) | CTSBCTSSCTSKCTSLCYP3A4 | |
| SCHEMBL6473457 | 0.82 | IDO1 (0.53) | CTSBCTSSCTSKCTSLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425009-A4 | PEPTIDE ARGINALS AND METHODS FOR TREATING DISSEMINATED INTRAVASCULAR COAGULATION | IVAX INST FOR DRUG RES LTD (HU) | 2006-10-25 | — | — | EP | disclosed |
| US-20050070480-A1 | Peptide arginals and methods for treating disseminated intravascular coagulation | IVAX DRUG RESEARCH INSTITUTE LTD. (HU) | 2005-03-31 | — | — | US | disclosed |
| EP-1425009-A2 | PEPTIDE ARGINALS AND METHODS FOR TREATING DISSEMINATED INTRAVASCULAR COAGULATION | Ivax Institute for Drug Research, Ltd. (HU) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003016273-A2 | PEPTIDE ARGINALS AND METHODS FOR TREATING DISSEMINATED INTRAVASCULAR COAGULATION | IVAX CORPORATION (US) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070480-A1 | Peptide arginals and methods for treating disseminated intravascular coagulation | ARGLU1, PLAT, SERPINC1 | CTSB 369/4885CTSS 590/4885CTSK 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.