Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.32 |
| ▸ | PLD2 | O14939 | 6/20 | 0.32 |
| ▸ | PLD1 | Q13393 | 6/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330586 | 0.92 | SLC6A9 (0.33) | SLC6A9PLD2PLD1CD274DRD2 | |
| SCHEMBL6447416 | 0.90 | KMT2A (0.36) | SLC6A9NAMPTPLD2PLD1MEN1 | |
| SCHEMBL5991907 | 0.88 | EPHX2 (0.37) | SLC6A9MEN1KMT2A | |
| SCHEMBL5992412 | 0.86 | PLD2 (0.34) | NAMPTPLD2PLD1CD274DRD2 | |
| SCHEMBL5988704 | 0.86 | PLD2 (0.34) | NAMPTPLD2PLD1CD274MEN1 | |
| SCHEMBL5990532 | 0.85 | NPC1 (0.36) | SLC6A9MEN1KMT2A | |
| SCHEMBL4558520 | 0.82 | PDPK1 (0.39) | SLC6A9PLD2PLD1MEN1KMT2A | |
| SCHEMBL3938534 | 0.78 | KDM4E (0.31) | MEN1KMT2A | |
| SCHEMBL4558093 | 0.78 | PLD2 (0.35) | PLD2PLD1CD274MEN1KMT2A | |
| SCHEMBL4331597 | 0.77 | L3MBTL1 (0.38) | DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661896-A1 | PYRROLOPYRIMIDINETHIONE DERIVATIVE | Teijin Pharma Limited (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-20050153992-A1 | Pyrrolopyrimidine thion derivatives | TEIJIN PHARMA LIMITED (JP) | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153992-A1 | Pyrrolopyrimidine thion derivatives | GSK3B, GSK3A, GSKIP | SLC6A9 3739/4885NAMPT 197/4885PLD2 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.