Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601137 | 0.85 | AKR1C3 (0.53) | AKR1C3TSHRPGK1PGK2IDO1 | |
| SCHEMBL735220 | 0.83 | AKR1C3 (0.44) | AKR1C3TSHRPGK1PGK2IDO1 | |
| SCHEMBL5331963 | 0.82 | AKR1C3 (0.67) | AKR1C3TSHRPGK1PGK2IDO1 | |
| SCHEMBL11378806 | 0.77 | AKR1C3 (0.46) | AKR1C3TSHRPGK1PGK2IDO1 | |
| SCHEMBL2374254 | 0.77 | AKR1C3 (0.42) | AKR1C3TSHRPGK1PGK2IDO1 | |
| SCHEMBL5983772 | 0.74 | AKR1C3 (0.81) | AKR1C3TSHRPGK1PGK2IDO1 | |
| SCHEMBL5069158 | 0.74 | AKR1C3 (1.00) | AKR1C3TSHRPGK1PGK2IDO1 | |
| SCHEMBL3625606 | 0.74 | TSHR (0.42) | AKR1C3TSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL35321 | 0.73 | CA1 (0.55) | AKR1C3TSHRCA1CA2CES2 | |
| SCHEMBL8600352 | 0.72 | IDO1 (0.39) | AKR1C3TSHRIDO1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9201067-B2 | Size-controlled macromolecule | POSCO (KR) | 2015-12-01 | — | — | US | disclosed |
| EP-1664341-B1 | SIZE-CONTROLLED MACROMOLECULE | POSCO (KR) | 2013-01-30 | — | — | EP | disclosed |
| EP-1664341-A2 | SIZE-CONTROLLED MACROMOLECULE | Posco (KR) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026191-A2 | SIZE-CONTROLLED MACROMOLECULE | POSCO (KR) | 2005-03-24 | — | — | WO | disclosed |
| US-20050037413-A1 | functionalized substrates bound to layers of dendrimers and to target-specific ligands, used in combinatorial chemistry, protein, nucleic acid or nucleic acid/peptide hybridization detection; medical diagnosis | POSCO (KR) | 2005-02-17 | — | — | US | disclosed |
| EP-0131993-B1 | PHOSPHORYLATING AGENT; A PROCESS FOR THE PREPARATION THEREOF; A PROCESS FOR PHOSPHORYLATING AN ORGANIC HYDROXYL OR AMINE COMPOUND | Stichting Katholieke Universiteit (NL) | 1988-05-25 | — | — | EP | disclosed |
| US-4293492-A | PHOTOCONDUCTIVITY, ELECTROGRAPHY, PIGMENT | RICOH CO., LTD. (JP) | 1981-10-06 | — | — | US | disclosed |
| US-4251614-A | CARBAZOLE DERIVATIVES | RICOH COMPANY, LTD. (JP) | 1981-02-17 | — | — | US | disclosed |