Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983777 | 0.83 | AKR1C3 (0.58) | AKR1C3TSHRCA1CA2CES2 | |
| SCHEMBL3625606 | 0.78 | TSHR (0.42) | AKR1C3TSHRKCNH2RAB9AMAPT | |
| SCHEMBL735219 | 0.75 | AKR1C3 (0.61) | AKR1C3TSHRKCNH2CA1CA2 | |
| SCHEMBL2374254 | 0.74 | AKR1C3 (0.42) | AKR1C3TSHRCA1CA2CES2 | |
| SCHEMBL27339909 | 0.73 | AKR1C3 (0.58) | AKR1C3TSHRKCNH2CA1CA2 | |
| Phosphonic Acid SCHEMBL5328144 | 0.73 | TSHR (0.38) | AKR1C3TSHRKCNH2RAB9AMAPT | |
| SCHEMBL8601137 | 0.72 | AKR1C3 (0.53) | AKR1C3TSHRCA1CA2RAB9A | |
| SCHEMBL4742687 | 0.72 | ALDH1A1 (0.37) | TSHRRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5983483 | 0.71 | AKR1C3 (0.56) | AKR1C3TSHRKCNH2CA1CA2 | |
| SCHEMBL35321 | 0.70 | CA1 (0.55) | AKR1C3TSHRCA1CA2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9201067-B2 | Size-controlled macromolecule | POSCO (KR) | 2015-12-01 | — | — | US | disclosed |
| EP-1664341-B1 | SIZE-CONTROLLED MACROMOLECULE | POSCO (KR) | 2013-01-30 | — | — | EP | disclosed |
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |
| US-20080064867-A1 | PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | SIGMA ALDRICH COMPANY (US) | 2008-03-13 | — | — | US | disclosed |
| US-7276598-B2 | Phosphorylation reagents for improved processes to convert terminal hydroxyl groups of oligonucleotides into phosphate monoesters | SIGMA-ALDRICH CO. (US) | 2007-10-02 | — | — | US | disclosed |
| EP-1664341-A2 | SIZE-CONTROLLED MACROMOLECULE | Posco (KR) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026191-A2 | SIZE-CONTROLLED MACROMOLECULE | POSCO (KR) | 2005-03-24 | — | — | WO | disclosed |
| US-20050037413-A1 | functionalized substrates bound to layers of dendrimers and to target-specific ligands, used in combinatorial chemistry, protein, nucleic acid or nucleic acid/peptide hybridization detection; medical diagnosis | POSCO (KR) | 2005-02-17 | — | — | US | disclosed |
| US-20040230047-A1 | Coupling phosphoramidites; phosphates removable in one deprotection step; solid phase synthesis | PROLIGO, LLC (US) | 2004-11-18 | — | — | US | disclosed |
| US-20030162957-A1 | Protected deoxyadenosines and deoxyguanosines | HONEYWELL INTERNATIONAL INC. | 2003-08-28 | — | — | US | disclosed |
| WO-2002068437-A9 | PROTECTED DEOXYADENOSINES AND DEOXYGUANOSINES | HONEYWELL INT INC (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002068437-A1 | PROTECTED DEOXYADENOSINES AND DEOXYGUANOSINES | HONEYWELL INTERNATIONAL, INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| US-6414137-B1 | Selective solvent extraction for the purification of protected nucleosides | ALLIEDSIGNAL INC. | 2002-07-02 | — | — | US | disclosed |
| EP-1140957-A1 | SELECTIVE SOLVENT EXTRACTION FOR THE PURIFICATION OF PROTECTED NUCLEOSIDES | AlliedSignal Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000075154-A2 | PROTECTED NUCLEOSIDES | ALLIEDSIGNAL INC. (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-2000039138-A1 | SELECTIVE SOLVENT EXTRACTION FOR THE PURIFICATION OF PROTECTED NUCLEOSIDES | ALLIEDSIGNAL INC. (US) | 2000-07-06 | — | — | WO | disclosed |
| US-5039796-A | Process for 5'-phosphorylation of nucleic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230047-A1 | Coupling phosphoramidites; phosphates removable in one deprotection step; solid phase synthesis | DIMT1, RNGTT, ADAR | AKR1C3 1381/4885TSHR 2080/4885KCNH2 4451/4885 |
| US-20080064867-A1 | PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | RNGTT, DUT, ADAR | AKR1C3 2130/4885TSHR 2956/4885KCNH2 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.