Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980868 | 1.00 | PTGS2 (0.49) | PTGS2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL8519336 | 0.98 | PTGS2 (0.48) | PTGS2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL8400694 | 0.93 | AR (0.50) | PTGS2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL29601087 | 0.93 | AR (0.50) | PTGS2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL6230783 | 0.86 | AR (0.47) | PTGS2TSHRKDM4EGAAAR | |
| SCHEMBL9644566 | 0.86 | MEN1 (0.44) | PTGS2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL7713273 | 0.86 | MEN1 (0.44) | PTGS2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL28524164 | 0.86 | MEN1 (0.44) | PTGS2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL27613330 | 0.84 | MEN1 (0.42) | PTGS2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL2552925 | 0.81 | TSHR (0.50) | PTGS2MEN1KMT2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675916-A1 | HEAT-STABLE DIKETOPYRROLOPYRROLE PIGMENT MIXTURES | Ciba SC Holding AG (CH) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005040284-A1 | HEAT-STABLE DIKETOPYRROLOPYRROLE PIGMENT MIXTURES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-05-06 | — | — | WO | disclosed |