Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3858544 | 0.83 | EPHX1 (0.40) | EPHX1ALDH1A1TP53EPHX2KDM4E | |
| SCHEMBL15219463 | 0.80 | SHBG (0.40) | EPHX1ALDH1A1EPHX2KDM4ENPSR1 | |
| SCHEMBL3858547 | 0.77 | LMNA (0.51) | EPHX1ALDH1A1EPHX2LMNASMN1; SMN2 | |
| SCHEMBL20943419 | 0.76 | EPHX1 (0.44) | EPHX1ALDH1A1TP53EPHX2KDM4E | |
| SCHEMBL28400955 | 0.74 | EPHX1 (0.43) | EPHX1ALDH1A1TP53EPHX2KDM4E | |
| SCHEMBL3858382 | 0.73 | ALDH1A1 (0.33) | EPHX1ALDH1A1EPHX2KDM4EMAPT | |
| SCHEMBL6536625 | 0.73 | EPHX1 (0.45) | EPHX1ALDH1A1EPHX2LMNAPMP22 | |
| SCHEMBL9609345 | 0.72 | TSHR (0.44) | EPHX1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11177572 | 0.72 | EPHX1 (0.52) | EPHX1ALDH1A1TP53KDM4EGMNN | |
| SCHEMBL10890511 | 0.72 | EPHX1 (0.41) | EPHX1ALDH1A1TP53EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144902-B1 | Prodrugs of thrombin inhibitors | ABBOTT GMBH & CO. KG (DE) | 2006-12-05 | — | — | US | disclosed |
| CN-1355810-A | Prodrugs of thrombin inhibitors | BASF AG (DE) | 2002-06-26 | — | — | CN | disclosed |