Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177836 | 0.87 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL18309237 | 0.86 | ALDH1A1 (0.70) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL1719399 | 0.86 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL8492777 | 0.84 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL18686247 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| Benzene SCHEMBL28101078 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1KMT2APOLB | |
| SCHEMBL960 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1KMT2APOLB | |
| SCHEMBL20351186 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL24384287 | 0.82 | ALDH1A1 (0.75) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL3730231 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058380-A1 | Novel aminobenzophenone compounds | OTTOSEN ERIK R | 2006-03-16 | — | — | US | disclosed |
| EP-1583735-A2 | NOVEL AMINOBENZOPHENONE COMPOUNDS | Leo Pharma A/S (DK) | 2005-10-12 | — | — | EP | disclosed |
| US-20050148648-A1 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED | 2005-07-07 | — | — | US | disclosed |
| US-6897236-B1 | Aminobenzophenones as inhibitors of IL-1β and TNF-α | LEO PHARMACEUTICAL PRODUCTS, LTD. (DK) | 2005-05-24 | — | — | US | disclosed |
| EP-1202959-B1 | AMINOBENZOPHENONES AS INHIBITORS OF IL-1-BETA AND TNF-ALPHA | LEO PHARMA AS (DK) | 2004-09-29 | — | — | EP | disclosed |
| WO-2004056762-A2 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA A/S (DK) | 2004-07-08 | — | — | WO | disclosed |
| US-20040030137-A1 | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148648-A1 | Modulators of ATP-binding cassette transporters | ABCB11, ABCB1, ABCC5 | ALDH1A1 895/4885MAPK1 3616/4885L3MBTL1 4414/4885 |
| US-20040030137-A1 | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands | DRD3, DRD2, DRD1 | ALDH1A1 1630/4885MAPK1 3993/4885L3MBTL1 3013/4885 |
| US-20060058380-A1 | Novel aminobenzophenone compounds | NFKBIA, IL4I1, ALDH7A1 | ALDH1A1 168/4885MAPK1 994/4885L3MBTL1 4618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.