Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274972 | 0.76 | ALOX5 (0.43) | ALOX5TRPV1TRIM24CYP11B2CYP11B1 | |
| SCHEMBL9275295 | 0.74 | ALOX5 (0.45) | ALOX5TRPV1TRIM24CYP11B2CYP11B1 | |
| SCHEMBL9271466 | 0.74 | ALOX5 (0.45) | ALOX5TRPV1TRIM24CYP11B2CYP11B1 | |
| SCHEMBL2107548 | 0.74 | ALOX5 (0.43) | ALOX5TRPV1TRIM24CYP11B2CYP11B1 | |
| SCHEMBL9100200 | 0.73 | ALOX5 (0.54) | ALOX5TRIM24CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL8979508 | 0.71 | ALOX5 (0.46) | ALOX5TRPV1TRIM24CYP11B2CYP11B1 | |
| SCHEMBL8979610 | 0.71 | ATAD2 (0.43) | ALOX5CYP11B2CYP11B1CYP1A2ALDH1A1 | |
| SCHEMBL8553346 | 0.71 | ALOX5 (0.46) | ALOX5TRPV1TRIM24CYP11B2CYP11B1 | |
| SCHEMBL8979497 | 0.70 | ALOX5 (0.36) | ALOX5TRPV1CYP11B2CYP11B1 | |
| SCHEMBL8979552 | 0.69 | ATAD2 (0.32) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718284-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFRACTION, STROKE, AND PAOD; METHODS OF TREATMENT | Decode Genetics EHF. (IS) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005075022-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFRACTION, STROKE, AND PAOD; METHODS OF TREATMENT | DECODE GENETICS EHF. (IS) | 2005-08-18 | — | — | WO | disclosed |