Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979552 | 0.90 | ATAD2 (0.32) | ATAD2ALOX5CHRM1CHRM2CHRM4 | |
| SCHEMBL8979490 | 0.83 | ATAD2 (0.42) | ATAD2CYP1A2CYP11B1CYP11B2DRD3 | |
| SCHEMBL8979601 | 0.78 | CYP11B1 (0.33) | CYP11B1CYP11B2ALOX5 | |
| SCHEMBL8979497 | 0.77 | ALOX5 (0.36) | CYP11B1CYP11B2ALOX5 | |
| SCHEMBL8979508 | 0.77 | ALOX5 (0.46) | CYP1A2CYP11B1CYP11B2ALOX5 | |
| SCHEMBL8979542 | 0.74 | TRPV1 (0.36) | CYP11B1CYP11B2ALOX5 | |
| SCHEMBL8979523 | 0.73 | CYP1A2 (0.34) | CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL8979613 | 0.73 | ATAD2 (0.40) | ATAD2CYP1A2CYP11B1CYP11B2ALOX5 | |
| SCHEMBL2108821 | 0.73 | ATAD2 (0.40) | ATAD2CYP1A2CYP11B1CYP11B2ALOX5 | |
| SCHEMBL5989847 | 0.71 | ALOX5 (0.42) | CYP1A2CYP11B1CYP11B2ALOX5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512594-A | ADMINISTERING TO TREAT A MEDICAL CONDITION MEDIATED BY ONE OR MORE LEUKOTRIENES | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |