Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13056606 | 0.87 | ADORA3 (0.36) | POLBUSP2TSHRALDH1A1CCNC | |
| SCHEMBL5201993 | 0.86 | GLA (0.36) | POLBUSP2TSHRGLAALDH1A1 | |
| SCHEMBL9283238 | 0.86 | GABRP (0.38) | POLBUSP2TSHRGLAKDM4C | |
| SCHEMBL11056691 | 0.84 | GLA (0.35) | POLBUSP2TSHRGLAALDH1A1 | |
| SCHEMBL11055751 | 0.83 | GLA (0.34) | POLBUSP2TSHRGLAKDM4C | |
| SCHEMBL7234563 | 0.82 | ALDH1A1 (0.39) | POLBUSP2TSHRGLAALDH1A1 | |
| SCHEMBL5990880 | 0.82 | MAPK1 (0.39) | POLBUSP2TSHRGLAALDH1A1 | |
| SCHEMBL7398766 | 0.81 | HPGD (0.37) | POLBUSP2TSHRGLAALDH1A1 | |
| SCHEMBL27318209 | 0.80 | GPR84 (0.38) | ALDH1A1GPR84GABRPGABRDGABRA1 | |
| SCHEMBL4356883 | 0.80 | ALDH1A1 (0.49) | POLBTSHRALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |