Benzo[B]Fluorene

Benzo[B]Fluorene

SCHEMBL599104

c1ccc2c(c1)Cc1cc3ccccc3cc1-2

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 3/20 0.55
MAPT P10636 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
HPGD P15428 3/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
LMNA P02545 1/20 0.55
CYP3A4 P08684 5/20 0.53
TSHR P16473 5/20 0.53
HSD17B10 Q99714 5/20 0.53
CYP2C9 P11712 4/20 0.53
TP53 P04637 3/20 0.53
MAPK1 P28482 3/20 0.53
CYP2D6 P10635 3/20 0.53
CYP2C19 P33261 3/20 0.53
PKM P14618 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
SRD5A2 P31213 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[B]Fluorene SCHEMBL30914260 1.00 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD
Benzo[B]Fluorene SCHEMBL29367443 1.00 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD
SCHEMBL4851856 0.96 SMN1; SMN2 (0.52) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD
SCHEMBL4851897 0.93 SMN1; SMN2 (0.57) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD
SCHEMBL1655232 0.91 MEN1 (0.46) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD
SCHEMBL30924248 0.91 MEN1 (0.46) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD
Anthracene SCHEMBL42657 0.88 ALDH1A1 (0.56) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD
Anthracene SCHEMBL20549190 0.86 ALDH1A1 (0.54) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD
Benz(B)Anthracene SCHEMBL29144751 0.86 ALDH1A1 (0.54) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD
SCHEMBL18582934 0.85 SMN1; SMN2 (0.64) ALDH1A1KDM4EMAPTSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608895-A1 HIGH TEMPERATURE DIELECTRIC POLYMERS AND FILMS The Scripps Research Institute (US) 2025-09-03 EP claimed
WO-2024091675-A1 HIGH TEMPERATURE DIELECTRIC POLYMERS AND FILMS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-05-02 WO claimed
WO-2024091684-A1 POLYSULFATE AND POLYSULFONATE POLYMERS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-05-02 WO claimed
CN-117567755-A Self-calibration fluorescent temperature sensing material suitable for low temperature and preparation method and application thereof 江苏联环药业股份有限公司 2024-02-20 CN claimed
WO-2023208837-A1 OLIGOMERIC BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2023-11-02 WO claimed
CN-116217408-A Organic electroluminescent compound, organic electroluminescent device and intermediate for synthesizing organic electroluminescent compound 阜阳欣奕华材料科技有限公司 2023-06-06 CN claimed
US-20180072863-A1 METHOD OF MAKING GRAPHENE COMPOSITIONS VORBECK MATERIALS CORP. (US) 2018-03-15 US claimed
EP-2260035-B1 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2014-08-20 EP claimed
US-8486312-B2 Photochromic naphthopyrans having a double-bridged terphenyl sub-unit RODENSTOCK GMBH (DE) 2013-07-16 US claimed
EP-2268629-B1 PHOTOCHROMIC NAPHTHOPYRANES HAVING A DOUBLE-BRIDGED TERPHENYL SUB-UNIT RODENSTOCK GMBH (DE) 2013-07-03 EP claimed
US-20060204202-A1 Fiber optic material and the use thereof FORSCHUNGSZINTRUM KARLSRUHE GMBH (DE) 2006-09-14 US claimed
WO-2006072798-A1 BISMUTH MEDIATED OXIDATIONS IC INNOVATIONS LIMITED (GB) 2006-07-13 WO claimed
US-6835296-B2 Electrochemical polymerization; polyfluorenone; light emitting diodes IM&T RESEARCH, INC. 2004-12-28 US claimed
US-6767446-B2 ELECTROLYTIC POLYMERIZATION OF AROMATIC HYDROCARBONS SUCH AS FLUORENE IN THE PRESENCE OF AN ESTER; OXIDIZING RESULTING POLYMER TO PRODUCE A CYCLOPENTANONE-CONTAINING POLYMER SUCH AS POLY(9-FLUORENONE); LIGHT EMITTING DIODES IM&T RESEARCH, INC. 2004-07-27 US claimed
WO-2003041519-A1 EXTRACTION METHOD FOR POLYAROMATIC HYDROCARBON ANALYSIS VECTOR TOBACCO INC. (US) 2003-05-22 WO claimed
US-20030081432-A1 Electrolytic polymerization of aromatic hydrocarbons such as fluorene in the presence of an ester; oxidizing resulting polymer to produce a cyclopentanone-containing polymer such as poly(9-fluorenone); light emitting diodes IM&T RESEARCH, INC. 2003-05-01 US claimed
US-20030066757-A1 Method for preparing polymers containing cyclopentanone structures IM&T RESEARCH, INC. 2003-04-10 US claimed
EP-0690752-B1 PROCESS FOR BIOREMEDIATION OF CONTAMINATED SOIL OR GROUNDWATER SBP TECHNOLOGIES INC (US) 1998-01-07 EP claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-4791231-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1988-12-13 US claimed