Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 10/20 | 0.47 |
| ▸ | ACACB | O00763 | 8/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10127533 | 0.89 | ACACA (0.54) | ACACAACACBITGB3ITGA2BOPRM1 | |
| Hydrochloric Acid SCHEMBL288169 | 0.88 | ACACA (0.53) | ACACAACACBITGB3ITGA2BOPRM1 | |
| SCHEMBL23460462 | 0.82 | ITGB3 (0.45) | ACACAACACBITGB3ITGA2BSSTR5 | |
| SCHEMBL25900708 | 0.80 | MMP2 (0.47) | ACACAACACBOPRM1OPRL1KCNH2 | |
| Hydrochloric Acid SCHEMBL31501396 | 0.79 | MMP2 (0.46) | ACACAACACBOPRM1OPRL1KCNH2 | |
| SCHEMBL10127543 | 0.78 | ACACA (0.45) | ACACAACACBITGB3ITGA2BOPRM1 | |
| SCHEMBL10127145 | 0.78 | ACACB (0.53) | ACACAACACBITGB3ITGA2BOPRM1 | |
| SCHEMBL25313921 | 0.78 | ACACB (0.51) | ACACAACACBITGB3ITGA2BOPRM1 | |
| Hydrochloric Acid SCHEMBL25314024 | 0.77 | ACACB (0.50) | ACACAACACBITGB3ITGA2BOPRM1 | |
| SCHEMBL289645 | 0.74 | ITGB3 (0.55) | ACACAACACBITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041012-A1 | SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME CORP. | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041012-A1 | SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS | SSTR5, SSTR2, GPR119 | ACACA 425/4885ACACB 475/4885ITGB3 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.