Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990020 | 0.82 | RAB9A (0.70) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL8711999 | 0.80 | TRPA1 (0.42) | RAB9ANPC1TLR7MAPTTRPA1 | |
| SCHEMBL8709730 | 0.78 | GSTA1 (0.61) | RAB9AHSD17B14NPC1KMT2AALDH1A1 | |
| SCHEMBL29994104 | 0.78 | GSTA1 (0.61) | RAB9AHSD17B14NPC1KMT2AALDH1A1 | |
| SCHEMBL4521629 | 0.77 | HNF4A (0.54) | GAAMAPK1KMT2AALDH1A1MEN1 | |
| SCHEMBL30070803 | 0.77 | HNF4A (0.54) | GAAMAPK1KMT2AALDH1A1MEN1 | |
| SCHEMBL30118935 | 0.76 | KMT2A (0.58) | RAB9AHSD17B14KMT2AALDH1A1LMNA | |
| SCHEMBL8710005 | 0.76 | KMT2A (0.58) | RAB9AHSD17B14KMT2AALDH1A1LMNA | |
| SCHEMBL3702884 | 0.76 | KDM4E (0.44) | RAB9ANPC1GAAKMT2AALDH1A1 | |
| SCHEMBL18557316 | 0.75 | KMT2A (0.53) | RAB9AHSD17B14NPC1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |