Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990019 | 0.85 | SRD5A2 (0.52) | SRD5A2CES2CNR1MAOBCNR2 | |
| SCHEMBL5989823 | 0.84 | PPARA (0.52) | SRD5A2CES2ALDH1A1POLBVNN1 | |
| SCHEMBL11357418 | 0.82 | CES2 (0.53) | SRD5A2CES2ALDH1A1CNR1MAPT | |
| SCHEMBL11524880 | 0.81 | KLKB1 (0.50) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL30070803 | 0.80 | HNF4A (0.54) | ALDH1A1MAPTHTTMEN1CYP1A2 | |
| SCHEMBL4521629 | 0.80 | HNF4A (0.54) | ALDH1A1MAPTHTTMEN1CYP1A2 | |
| SCHEMBL14419285 | 0.80 | TMPRSS4 (0.62) | SRD5A2CES2CNR1VNN1MEN1 | |
| SCHEMBL5990096 | 0.76 | LMNA (0.42) | CNR2 | |
| SCHEMBL5991790 | 0.75 | MAPT (0.49) | ALDH1A1CNR1MAPTHTTMEN1 | |
| SCHEMBL1237189 | 0.74 | SRD5A2 (0.79) | SRD5A2CES2ALDH1A1POLBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |