Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.50 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.50 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521629 | 0.88 | HNF4A (0.54) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL30070803 | 0.88 | HNF4A (0.54) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL5992299 | 0.81 | SRD5A2 (0.49) | ALDH1A1CNR2MEN1MAPTKMT2A | |
| SCHEMBL9417853 | 0.81 | SHBG (0.47) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL418713 | 0.79 | KLKB1 (0.71) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL46935 | 0.77 | BCL2 (0.66) | BCL2ALDH1A1FOLH1 | |
| SCHEMBL30394310 | 0.77 | BCL2 (0.66) | BCL2ALDH1A1FOLH1 | |
| SCHEMBL11527296 | 0.77 | SRD5A2 (0.50) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL25245771 | 0.76 | LIG1 (0.56) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL21486417 | 0.76 | KAT8 (0.54) | KLKB1CTSBMMP9DNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141995-A | Ketone derivatives | LILLY INDUSTRIES LIMITED (GB) | 1979-02-27 | — | — | US | disclosed |