SCHEMBL599443

SCHEMBL599443

CCCC(Nc1ncnc(NC(CCC)C2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)n1)C1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPR3 P17342 2/20 0.32
IDH1 O75874 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1231052 0.93 IDH1 (0.31) IDH1
SCHEMBL8653402 0.93
SCHEMBL5691607 0.91
SCHEMBL9428260 0.88
SCHEMBL456758 0.88 IDH1 (0.32) IDH1
SCHEMBL1005117 0.86 IDH1 (0.30) IDH1
SCHEMBL9210643 0.85
SCHEMBL9207772 0.85 ADAMTS5 (0.33)
SCHEMBL78005 0.85 CDK1 (0.33)
SCHEMBL607239 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1551914-B1 FLAME RETARDANT POLYMERIC ELECTRICAL PARTS CIBA SC HOLDING AG (CH) 2006-08-09 EP claimed
US-10072128-B2 Polyolefin-based resin pre-expanded particles and polyolefin-based resin in-mold expansion molded article comprising polyolefin-based resin pre- expanded particles KANEKA CORPORATION (JP) 2018-09-11 US disclosed
EP-2743295-B1 POLYOLEFIN RESIN FOAM PARTICLES AND IN-MOLD FOAMING MOLDED BODY OF SAME KANEKA CORP (JP) 2016-04-27 EP disclosed
US-9249281-B2 Polyolefin resin foam particles and in-mold foaming molded body of same KANEKA CORPORATION (JP) 2016-02-02 US disclosed
US-20150210815-A1 POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN-BASED RESIN IN-MOLD EXPANSION MOLDED ARTICLE COMPRISING POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES KANEKA CORPORATION (JP) 2015-07-30 US disclosed
EP-2420533-B1 POLYOLEFIN RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN RESIN IN-MOLD EXPANSION-MOLDED ARTICLE COMPRISING POLYOLEFIN RESIN PRE-EXPANDED PARTICLES KANEKA CORP (JP) 2014-12-31 EP disclosed
US-20140171534-A1 POLYOLEFIN RESIN FOAM PARTICLES AND IN-MOLD FOAMING MOLDED BODY OF SAME KANEKA CORPORATION (JP) 2014-06-19 US disclosed
EP-2743295-A1 POLYOLEFIN RESIN FOAM PARTICLES AND IN-MOLD FOAMING MOLDED BODY OF SAME Kaneka Corporation (JP) 2014-06-18 EP disclosed
EP-2420533-A1 POLYOLEFIN RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN RESIN IN-MOLD EXPANSION-MOLDED ARTICLE COMPRISING POLYOLEFIN RESIN PRE-EXPANDED PARTICLES Kaneka Corporation (JP) 2012-02-22 EP disclosed
US-20120037837-A1 POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN-BASED RESIN IN-MOLD EXPANSION MOLDED ARTICLE COMPRISING POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES KANEKA CORPORATION (JP) 2012-02-16 US disclosed
EP-1454947-B1 FLAME RETARDANT POLYOLEFIN RESIN PRE-EXPANDED PARTICLES AND IN-MOLD FOAMED ARTICLES PREPARED THEREFROM KANEKA CORP (JP) 2010-02-17 EP disclosed
US-6822023-B2 MIXTURE CONTAINING STERIC HINDERED OXYAMINE COMPOUND KANEKA CORPORATION (JP) 2004-11-23 US disclosed
EP-1454947-A1 PRE−EXPANDED BEADS OF FLAME−RETARDANT POLYOLEFIN RESIN AND MOLDED OBJECT THEREOF BY IN−MOLD FOAMING KANEKA CORPORATION (JP) 2004-09-08 EP disclosed
US-20030105194-A1 Flame retardant polyolefin resin pre-expanded particles and in-mold foamed articles prepared therefrom KANEKA CORPORATION (JP) 2003-06-05 US disclosed