Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209345 | 0.86 | HDAC2 (0.56) | CYP3A4TSHRHDAC2KMT2AMEN1 | |
| SCHEMBL4212550 | 0.84 | CYP3A4 (0.76) | CYP3A4TSHRHDAC2KMT2AMEN1 | |
| SCHEMBL4214098 | 0.84 | CYP3A4 (0.54) | CYP3A4TSHRHDAC2KMT2AMEN1 | |
| SCHEMBL4199189 | 0.83 | CYP3A4 (0.73) | CYP3A4TSHRHDAC2KMT2AMEN1 | |
| SCHEMBL4215625 | 0.81 | ALDH1A1 (0.57) | CYP3A4TSHRHDAC2KMT2AMEN1 | |
| SCHEMBL4211607 | 0.79 | ALDH1A1 (0.76) | CYP3A4TSHRHDAC2KMT2AMEN1 | |
| SCHEMBL4206360 | 0.79 | HDAC2 (0.58) | CYP3A4TSHRHDAC2KMT2AMEN1 | |
| SCHEMBL5995926 | 0.78 | CYP3A4 (0.59) | CYP3A4TSHRKMT2AMEN1CYP1A2 | |
| SCHEMBL4203822 | 0.77 | TSHR (0.76) | CYP3A4TSHRKMT2AMEN1CYP1A2 | |
| SCHEMBL4209470 | 0.77 | LMNA (0.56) | CYP3A4TSHRHDAC2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060100235-A1 | Pharmaceutical use of substituted 1,2,4-triazoles | NOVO NORDISK A/S (DK) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100235-A1 | Pharmaceutical use of substituted 1,2,4-triazoles | HSD3B1, HSD11B1, HSD3B2 | CYP3A4 48/4885TSHR 2592/4885HDAC2 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.