SCHEMBL5995192

SCHEMBL5995192

CCP(=O)(C(=O)c1c(C)cc(C(C)(C)C)cc1C)C(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
GAA P10253 3/20 0.40
MAPT P10636 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KCNJ6 P48051 1/20 0.39
KCNJ5 P48544 1/20 0.39
KCNJ3 P48549 1/20 0.39
ALDH1A1 P00352 2/20 0.36
NPC1 O15118 1/20 0.36
GLA P06280 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PTGS2 P35354 1/20 0.36
POLB P06746 2/20 0.35
TYK2 P29597 2/20 0.35
LMNA P02545 1/20 0.35
ACHE P22303 1/20 0.33
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
ESRRB O95718 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995846 0.89 SMN1; SMN2 (0.37) RAB9AALDH1A1LMNAACHEF2R
SCHEMBL5995866 0.88 ACLY (0.35) RAB9AGAAMAPTL3MBTL1POLB
SCHEMBL5996306 0.87 KMT2A (0.43) RAB9AGAAMAPTALDH1A1POLB
SCHEMBL5994505 0.87 RAB9A (0.38) RAB9AGAAMAPTNPSR1KCNJ6
SCHEMBL5993532 0.87 HPGD (0.39) RAB9AALDH1A1POLBKMT2AMEN1
SCHEMBL5994380 0.86 GAA (0.38) RAB9AGAAMAPTNPSR1KCNJ6
SCHEMBL5996451 0.86 TYK2 (0.46) RAB9AALDH1A1TYK2KMT2A
SCHEMBL5994046 0.85 GABRA1 (0.36) RAB9AMAPTKCNJ6KCNJ5KCNJ3
SCHEMBL29933904 0.84 ALDH1A1 (0.47) RAB9AGAAMAPTALDH1A1NPC1
SCHEMBL5995818 0.83 HPGD (0.39) RAB9AMAPTALDH1A1NPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 RAB9A 3300/4885GAA 4801/4885MAPT 4713/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 RAB9A 1141/4885GAA 4108/4885MAPT 4813/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 RAB9A 2807/4885GAA 4741/4885MAPT 4467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.