Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 6/20 | 0.49 |
| ▸ | CHUK | O15111 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997842 | 0.84 | KDR (0.52) | ABL1SRC | |
| Hydrochloric Acid SCHEMBL5999389 | 0.83 | KDR (0.51) | ABL1SRC | |
| SCHEMBL5996220 | 0.78 | SRC (0.56) | LMNAALDH1A1KDM4EGFERABL1 | |
| SCHEMBL5995458 | 0.78 | SRC (0.56) | LMNAALDH1A1KDM4EGFERABL1 | |
| SCHEMBL5996242 | 0.77 | ALDH1A1 (0.48) | LMNAALDH1A1KDM4EGFERABL1 | |
| SCHEMBL5997830 | 0.75 | TGM2 (0.52) | ALDH1A1KDM4EKMT2AF13A1TGM2 | |
| SCHEMBL5998458 | 0.75 | MAPK14 (0.56) | ABL1SRC | |
| SCHEMBL2498483 | 0.75 | BTK (0.51) | LMNAALDH1A1ABL1SRC | |
| SCHEMBL2498581 | 0.75 | BTK (0.47) | LMNAALDH1A1ABL1SRCIKBKB | |
| SCHEMBL14490343 | 0.74 | IKBKB (0.47) | ABL1SRCIKBKBCHUKF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247250-A1 | Pyrimidine inhibitors of kinases | TARGEGEN, INC. (US) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247250-A1 | Pyrimidine inhibitors of kinases | DTYMK, SRC, DCK | LMNA 4816/4885ALDH1A1 3321/4885KDM4E 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.