SCHEMBL5995457

SCHEMBL5995457

C=C(C[Si](C)(C)C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.47
MAOB P27338 6/20 0.47
EGFR P00533 2/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.36
XBP1 P17861 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12997576 0.84 ACHE (0.34) MAOAMAOBMEN1KMT2AATM
SCHEMBL3747872 0.83 MAOA (0.48) MAOAMAOBEGFRMAPTALDH1A1
SCHEMBL28598605 0.78 MAOA (0.44) MAOAMAOBMAPTMEN1KMT2A
SCHEMBL28916093 0.78 MAOA (0.50) MAOAMAOBMAPTALDH1A1LMNA
SCHEMBL28583017 0.78 MAOA (0.50) MAOAMAOBLMNASMN1; SMN2
SCHEMBL8189072 0.78 MAOA (0.48) MAOAMAOBEGFRMAPTALDH1A1
SCHEMBL8383505 0.78 MAOA (0.44) MAOAMAOBEGFRMAPTALDH1A1
SCHEMBL16687344 0.78 SMN1; SMN2 (0.32) ATMSMN1; SMN2
SCHEMBL3183060 0.77 MAOA (0.52) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL28059511 0.77 MAOA (0.42) MAOAMAOBEGFRMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024349-A 3, 3-difluoro-1, 5-hexadiene compound and preparation method and application thereof 南京工业大学 2021-06-25 CN claimed
JP-62209117-A None JP disclosed
EP-4495125-A1 A CATALYST FREE SYNTHESIS METHOD FOR INTRODUCING A TRIFLUOROMETHOXY MOIETY INTO AT LEAST ONE ORGANIC COMPOUND Freie Universität Berlin (DE) 2025-01-22 EP disclosed
CN-113024349-B 3, 3-difluoro-1, 5-hexadiene compound and preparation method and application thereof 南京工业大学 2022-06-07 CN disclosed
CN-113024349-A 3, 3-difluoro-1, 5-hexadiene compound and preparation method and application thereof 南京工业大学 2021-06-25 CN disclosed
US-8809567-B2 Method for producing silylenol ethers KYOTO UNIVERSITY (JP) 2014-08-19 US disclosed
US-8809567-B2 Method for producing silylenol ethers KYOTO UNIVERSITY (JP) 2014-08-19 US disclosed
US-8809567-B2 Method for producing silylenol ethers KYOTO UNIVERSITY (JP) 2014-08-19 US disclosed
US-20130053567-A1 METHOD FOR PRODUCING SILYLENOL ETHERS KYOTO UNIVERSITY (JP) 2013-02-28 US disclosed
US-20130053567-A1 METHOD FOR PRODUCING SILYLENOL ETHERS KYOTO UNIVERSITY (JP) 2013-02-28 US disclosed
WO-1999020267-A1 FURANYL, TETRACYCLIC TRITERPENE DERIVATIVES WITH IMMUNOSUPPRESSANT ACTIVITY MERCK & CO., INC. (US) 1999-04-29 WO disclosed
WO-1999020274-A1 TETRACYCLIC TRITERPENE DERIVATIVES WITH IMMUNOSUPPRESSANT ACTIVITY MERCK & CO., INC. (US) 1999-04-29 WO disclosed
US-5879855-A PIGMENT PRECURSOR DISSOLVED IN COMPOSITION WHICH CAN BE TRANSFORMED TO INSOLUBLE PIGMENT, POSITIVE OR NEGATIVE PHOTORESIST WHICH CAN BE MODIFIED CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-03-09 US disclosed
US-5871670-A Electroconductive composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-02-16 US disclosed
US-5830267-A Coloration of high molecular weight organic materials in the mass with soluble phthalocyanine precursors CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-11-03 US disclosed
EP-0782750-A1 NOVEL ELECTROCONDUCTIVE COMPOSITION Ciba SC Holding AG (CH) 1997-07-09 EP disclosed
EP-0742255-A1 Colouration of high molecular weight organic materials in the mass with soluble phthalocyanine precursors CIBA-GEIGY AG (CH) 1996-11-13 EP disclosed
WO-1996009629-A1 NOVEL ELECTROCONDUCTIVE COMPOSITION CIBA SPECIALTY CHEMICALS HOLDIING INC (CH) 1996-03-28 WO disclosed
EP-0654711-A1 Compositions for making structured color images and application thereof CIBA-GEIGY AG (CH) 1995-05-24 EP disclosed
JP-S62209117-A NOVEL COPOLYMER AND PRODUCTION THEREOF TSURUTA TEIJI 1987-09-14 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130053567-A1 METHOD FOR PRODUCING SILYLENOL ETHERS AKR7A2, MSMO1, CYP2E1 MAOA 2523/4885MAOB 2747/4885EGFR 2118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.