Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995457 | 0.78 | MAOA (0.47) | MAOAMAOBALDH1A1MAPTATM | |
| SCHEMBL3747872 | 0.75 | MAOA (0.48) | MAOAMAOBALDH1A1MAPTCES2 | |
| SCHEMBL31615018 | 0.75 | KMT2A (0.52) | ALDH1A1MAPTCES2CES1 | |
| SCHEMBL14958 | 0.75 | MAOA (0.52) | MAOAMAOBALDH1A1MAPTATM | |
| SCHEMBL27656482 | 0.75 | ALDH1A1 (0.41) | MAOAMAOBALDH1A1MAPTATM | |
| SCHEMBL3183060 | 0.74 | MAOA (0.52) | MAOAMAOBALDH1A1MAPTCES1 | |
| SCHEMBL28059511 | 0.73 | MAOA (0.42) | MAOAMAOBALDH1A1MAPTEGFR | |
| SCHEMBL78217 | 0.71 | CES2 (0.52) | MAOAMAOBATMCES2CES1 | |
| SCHEMBL29141677 | 0.70 | ATM (0.40) | MAOAMAOBALDH1A1MAPTATM | |
| SCHEMBL7990104 | 0.69 | MAOA (0.56) | MAOAMAOBALDH1A1MAPTCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100293-A | ANTIINFLAMMATORY AGENT EFFECTIVE IN THE PROPHYLAXIS OF ORGAN TRANSPLANT REJECTION; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-08-08 | — | — | US | disclosed |