SCHEMBL5996325

SCHEMBL5996325

Cc1cccc(C)c1C(=O)[P](=O)C(C)C(=O)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.34
FABP3 P05413 1/20 0.33
FABP4 P15090 1/20 0.33
NPSR1 Q6W5P4 3/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
S1PR2 O95136 2/20 0.33
S1PR4 O95977 2/20 0.33
S1PR3 Q99500 2/20 0.33
S1PR5 Q9H228 2/20 0.33
TYK2 P29597 1/20 0.33
KMT2A Q03164 2/20 0.32
UTS2R Q9UKP6 1/20 0.32
MAPT P10636 1/20 0.32
IDH1 O75874 1/20 0.32
ITGB1 P05556 2/20 0.31
ITGA4 P13612 2/20 0.31
CYP2C19 P33261 2/20 0.31
ITGA2 P17301 1/20 0.31
ITGB7 P26010 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5996465 0.90 TYK2 (0.40) FABP3FABP4TYK2UTS2RITGB1
SCHEMBL5996630 0.87 RAPGEF4 (0.34) NPSR1LMNAHTTKMT2AMAPT
SCHEMBL5995876 0.84 ACLY (0.33) KMT2AACLYCHRNA1CHRNGCHRNB1
SCHEMBL6402780 0.83 MEN1 (0.39) NPSR1LMNATYK2KMT2AMAPT
SCHEMBL5995806 0.83 CA12 (0.40) FABP4NPSR1LMNAHTTS1PR2
SCHEMBL5997547 0.81 HPGD (0.37) NPSR1LMNAKMT2AMEN1GPR52
SCHEMBL6402169 0.81 HPGD (0.37) NPSR1LMNAKMT2AMEN1GPR52
SCHEMBL5995203 0.80 RAB9A (0.36) NPSR1TYK2MAPTCYP2C19CHRNA1
SCHEMBL5995853 0.78 ACHE (0.36) MRGPRX4MAPTCYP3A4GPR52
SCHEMBL5997841 0.78 ACHE (0.36) MRGPRX4MAPTCYP3A4GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 MRGPRX4 3110/4885FABP3 3788/4885FABP4 3705/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 MRGPRX4 2754/4885FABP3 4397/4885FABP4 3862/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 MRGPRX4 2582/4885FABP3 4336/4885FABP4 3747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.